Product Name: Ivermectin 

Appearance: white crystalline powder 

CAS No.:70288-86-7 

EINECS No: 274-536-0

Molecular Formular: C95H146O28

Molecular Weight: 1736.16

Purity:99%

Solubility: soluble in acetone, very slightly soluble in hot water and n-octanol, insoluble in cold water and methanol.

Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod,
canine intestinal nematodes, ear mites, scabies mites, silkworm and microfilariae, gastrointestinal nematodes and external
parasites, and poultry. This product belongs to the broad-spectrum drug-resistant parasites.

Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine
ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane,
cause nerve cells or muscle cells hyperpolarization, parasites paralysis, or death.

1. Ivermectin is the derivative of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug-resistant parasites.  
2. Ivermectin has an effect on most of the various life cycle nematodes.  
3. Ivermectin has an effect on the microfilaria of onchocerca volvulus, but it does not have an effect on the adult onchocerca volvulus  
4. Ivermectin has an effect on dung roundworms that only stay in the intestinal tract  
5. Ivermectin has selective inhibition.  
6. Ivermectin can not go through the blood-brain barrier of human beings.

In veterinary medicine, ivermectin is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite
this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult
heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic
in over-dosage.

It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog
breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have
a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly
sensitive to the toxic effects of ivermectin. 

Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating
ear mites in cats are available.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in
some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly
contraindicated.