Factory Pharma Grade Anti Cancer Peptide Cetrorelix Acetate CAS 120287-85-6 in Stock

Product Information


Product Description
Cetrorelix (INN, BAN), or cetrorelix acetate (USAN, JAN), sold under the brand name Cetrotide, is an injectable gonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, it is used in assisted reproduction to inhibit premature luteinizinghor mone surges The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizinghor mone (LH) and follicle-stimulating hormone (FSH). In addition, cetrorelix can be used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). It is administered as either multiple 0.25 mg daily subcutaneous injections or as a single-dose 3 mg subcutaneous injection. The duration of the 3 mg single dose is four days; if human chorionic gonadotropin (hCG) is not administered within four days, a daily 0.25 mg dose is started and continued until hCG is administered.

Medical Uses

Cetrorelix is marketed by Merck Serono for use in in-vitro fertilization in all countries except Japan, where it is marketed by Shionogi and Nippon Kayaku. Aeterna Zentaris receives royalties on these sales and retains rights to develop cetrorelix for other indications. In IVF use it is injected daily after follicle stimulation has been initiated and evidence of follicle maturation is approaching; given daily it prevents an endogenous LH surge that would trigger an untimely ovulation prior to the hCG administration by the treating physician. As an alternative to the GnRH antagonist, also a GnRH agonist could be given, but agonist have to be started earlier to overcome the agonistic effect. Cetrorelix can be mixed with follitropin alpha without compromising their reported safety and efficacy.

Over a period of 3 weeks, daily injections of cetrorelix were administered to 12 men in order to suppress testoster one levels. Testoster one levels were significantly suppressed as compared to a control group. During this time of suppression, increases in high density lipoproteins (HDLs) were seen. HDLs are responsible for removing cholesterol from the blood and higher amounts are correlated with increased cardiovascular health.

Application
Cetrorelix acetate is a synthetic decapeptide, which is mainly used in assisted reproductive technology to prevent premature ovulation in patients with controlled ovarian stimulation. Cetrorelix acetate is also often called cetrorelix. It is a gonadotropin-releasing Chemicalbook radio-hormone (GnRH) antagonist, which can competitively bind to the receptors on the pituitary cell membrane with endogenous LHRH, thereby inhibiting the pituitary from secreting luteinizing horm one (LH) and follicle stimulating hormone (FSH). Dependence.
 

Specification

Our Service

 1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
 2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
 3.We can send the goods to your delivery address directly. It is relatively safe and fast. 
 4.Quick and clear response to customers questions.
 5.We could make our price discount if you place a substantial order with us.

Why Choose Us?

1.Full experience of large numbers containers loading in Chinese sea port.
2.Fast shipment by reputed shipping line.
3.Packing with pallet as buyer's special request.
4.Best service after shipment with e mail.
5.Cargoes together with container sales service available.
6.Full experience for Canada & Japan export.
7.Cargoes photo before and after loading into container.
8.Raw materials from Chinese origin.

Packaging Details:25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double
plastic bag insideDelivery Detail: within 3 days when get the payment.Shipping :
We have Professional shipping agent, based on customers ' demand for transport
By express :FEDEX,DHL,EMS ,UPS,TNT ect.
By SEA and By AIR

1:Can I get some samples before bulk order?
Yes, we can supply the free sample, but the shipping cost be paid by customers.
 

2: How to start orders or make payments?
PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C, Alibaba trade assurance, Moneygram or Bitcoin.
 

3: What's your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid. It depends on the product.
 

4: How about delivery leadtime?
Delivery lead time: About 3-5 workdays after payment confirmed.
 

5: How to contact us ?
You can chat with us by Trademanager,WhatsApp&Skype Online. You can dial our telephone directly or send E-mail to us and you will get our reply
 

6: How to confirm the Product Quality before placing orders?
You can get samples for the product you interest. Or you can send us your product specifications and requests,we will manufacture the products according to your requests.