China Hot Sale Bulk Price Skin Whitening Cosmetic Material Tranexamic Acid CAS 1197-18-8 Tranexamic Acid Powder Amstat, Find details about China Amstat, CAS 1197-18-8 from Hot Sale Bulk Price Skin Whitening Cosmetic Material Tranexamic Acid CAS 1197-18-8 Tranexamic Acid Powder Amstat
Product name | Tranexamic Acid |
CAS No | 1197-18-8 |
Appearance | White powder |
Purity | 99% |
Molrcular Formular | C8H15NO2 |
Tranexamic acid is a synthetic derivative of the amino acid lysine. It is used to treat or prevent excessive blood loss during surgery and in various other medical conditions. It is anantifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, by binding to specific sites of both plasminogen and plasmin, a molecule responsible for the degradation of fibrin, a protein that forms the framework of blood clots.
1.Post-partum bleeding
A large, international study was conducted on the use of tranexamic acid after childbirth to prevent hemorrhaging. The trial found that tranexamic acid significantly reduced the risk of death from hemorrhaging after childbirth.
2.Mouthwash for oral procedures
An antifibrinolytic mouthwash can be used for controlling bleeding after an oral procedure such as a tooth extraction. The tranexamic acid mouthwash is used prior to the procedure and immediately afterwards to prevent and reduce bleeding.
3.Nose bleeds
A topically applied tranexamic acid solution can help reduce nose bleeds.
4.Melasma
Topically applied tranexamic acid has been shown to significantly improve the appearance of melasma.
Specification
Items of Test | Standard as per BP2009 | Result |
CHARACTERS | Appearance: White or almost white, crystalline powder | Positive |
| Solubility: Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and in alcohol (96%). | Positive |
IDENTIFICATION | Infrared Absorption Spectrophotometry (2.2.24): IR spectrum is in concordance with Tranexamic acid CRS | Positive |
PH (2.2.3) | 0.05g/ml aqueous (carbon dioxide free water) solution, 7.0 to 8.0 | 7.3 |
Related substances Liquid chromatography (2.2.29) | Impurity A: NLT 0.1% | < 0.10% |
| Impurity B: NLT0.2% | < 0.20% |
| Unspecified impurities NLT0.10% | < 0.10% |
| Sum of unspecified impurities NLT 0.2% | < 0.20% |
Chlorides (2.4.4) | NLT140ppm | < 140ppm |
Heavy metals (2.4.8) | NLT 10ppm | < 10ppm |
Loss on drying (2.2.32) | NLT 0.5% | 0.3% |
Sulphated ash (2.4.14) | ≤ 0.1% | <0.1% |
ASSAY (titration 2.2.20) | 99.0% - 101.0% of C8H15NO2 (dried) | 99.6% |