China Cosmetic Raw Whitening and Light Spot Tranexamic Acid CAS: 1197-18-8 Good Stability Easy to Absorb, Find details about China Tranexamic Acid, 1197-18-8 from Cosmetic Raw Whitening and Light Spot Tranexamic Acid CAS: 1197-18-8 Good Stability Easy to Absorb
Tranexamic acid is a protease inhibitor that inhibits the catalytic action of proteas-es on peptide bond hydrolysis, thereby preventing the activity of enzymes such as inflammatory proteas-es and thereby inhibiting the chaos of epidermal cell function at the site of dark spots and inhibiting melanin Enhance the factor group, and then completely cut off because of UV irradiation and the formation of melanin way, that dark spots no longer thicken, expand and increase, which can effectively prevent and improve skin pigmentation.
Tranexamic acid compared with the traditional whitening ingredients can be expressed in a stable, high temperature production environment does not require the protection of various types of carrier transmission, still can achieve whitening effect, no irritating effect.
Tranexamic acid helps to spot effectively and rapidly, which helps to show perfect fair complexion and bright skin. Its melatonin stain effect than vitamin C about 50 times higher, is about 10 times the acid AHA. Concentration limit of 2% -3%, in cosmetics is about 0.5%. Therefore, it is widely used in a series of whitening products that prevent melanin from forming pigmentation spots.
Functions
1.Trauma
2.Heart surgery
3.Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin.
4.Orthopedic surgery
Menstrual bleeding
5.Dentistry
6.In hemophilia
Tranexamic acid is also useful in the treatment of bleeding as a second line treatment after factor VIII in patients (e.g. tooth extraction).
7.Whitening effect
Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%.
Application
1.Menstrual bleeding of Pure Tranexamic Acid
2.Orthopedic Surgery of Pure Tranexamic Acid
3.Trauma of Pure Tranexamic Acid
4.Dentistry of Pure Tranexamic Acid
5.In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with
6.In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
7.Whitening effect.Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%.
COA
Basic information | ||||
Product Name | Amstat |
| ||
CAS No. | 1197-18-8 | |||
Molecular formula | C8H15NO2 | |||
Molecular weight | 157.21 | |||
EINECS | 214-071-2 | |||
Batch Number | AM200723 | |||
Date of Certificate | April 25th, 2020 | |||
Standard Item | Specification | Test Results | ||
Appearance | White crystalline powder | Confirm | ||
Identification | A.H-NMR:Comply with the structure | Complies | ||
B.LC-MS:Comply with the structure | Complies | |||
C.The IR spectrum of sample should be identical with that of reference standard; | Complies | |||
D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Complies | |||
Crystallinity | Meets the requirements. | Complies | ||
Loss on drying | ≤1.0% | 0.85% | ||
Heavy metals | ≤10 ppm | <10ppm | ||
Water | ≤1.0% | 0.1% | ||
Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% | ||
Related substances | Unspecified impurities: for each impurity | ≤0.10% | <0.10% | |
Total Impurity | ≤0.5% | 0.18% | ||
Mass | 203.67±1 | Conforms | ||
NMR | Comply with the structure | Conforms | ||
Purity | ≥99.0% | 99.29% | ||
Assay | 99.0%~101.0% (anhydrous substance). | 99.63% | ||
Microbiological Analysis | ||||
Total plate count | ≤1000cfu/g | Complies | ||
Yeast and Moulds | ≤100cfu/g | Complies | ||
E. Coli. | Absent | Negative | ||
Salmonella | Absent | Negative | ||
S.aureus | Absent | Negative | ||
Storage | Preserve in well-closed, light-resistant and airtight containers. | |||
Retest date | Two years under conditions list above | |||
Conclusion | Conform with Conform with specification |