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Common Name | Orlistat | ||
---|---|---|---|
CAS Number | 96829-58-2 | Molecular Weight | 495.735 |
Density | 1.0±0.1 g/cm3 | Boiling Point | 615.9±30.0 °C at 760 mmHg |
Molecular Formula | C29H53NO5 | Melting Point | <50ºC |
Product Name: | Orlistat |
Synonyms: | (S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER;RO-18-0647;Orlistat Tablets;(-)-TETRAHYDROLIPSTATIN;ORLISTAT;N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER;XENICAL;(-)-Tetrahydrolipstatin(EquivalentToOrlistat) |
CAS: | 96829-58-2 |
MF: | C29H53NO5 |
MW: | 495.73 |
EINECS: | 639-755-1 |
Product Categories: | Pharmaceutical Raw Materials;Miscellaneous Biochemicals;API;Antiobesity Agent;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Heterocycles;ACTOS;Other APIs;Lipid-lowering medicine reducing weight |
Mol File: | 96829-58-2.mol |
Orlistat Chemical Properties |
Melting point | <50 °C |
alpha | D20 -32.0° (c = 1 in chloroform) |
Boiling point | 615.9±30.0 °C(Predicted) |
density | 0.976±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: 19 mg/mL |
form | solid |
pka | 14.59±0.23(Predicted) |
color | white |
Item | Specification | Result |
Appearance | while powder | white powder |
Identification | HPLC retention time | Conforms |
Melting Point | 42 ºC -45°C | 42 ºC -45°C |
Specific optical rotation | -31.0°~-41.0° | -36.0° |
Purity optical rotation | -31.0°~-41.0° | -36.0° |
Total impurity | no more than 2.0% | 1.6% |
Max Individual impurity | no more than 0.5% | 0.3% |
Water content%(K&F) | no more than 0.5% | 0.1% |
Residual solvents | EtOH no more than 0.5% | N.D |
EtAC no more than 0.5% | N.D | |
n-Heptane no more than 0.5% | less than 0.1% | |
Residue on ignition | less than 0.2% | 0.10% |
Heavy metals | no more than 20ppm | less than20ppm |
Assay (HPLC) | no less than 99.0% | 99.60% |
Conclusion | Meets the Requirements |
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