High Purity Gw-0742/Gw0742 Powder CAS 317318-84-6 at Factory Price with Guaranteed Safe Delivery

China High Purity Gw-0742/Gw0742 Powder CAS 317318-84-6 at Factory Price with Guaranteed Safe Delivery, Find details about China Gw0742, Gw-0742 from High Purity Gw-0742/Gw0742 Powder CAS 317318-84-6 at Factory Price with Guaranteed Safe Delivery

Model NO.
MSK55654654
Packaging
We Can Do Sub-Packaging Per Client′s Requirement
Delivery Promise
Reship Policy to Guarantee The Delivery Safety
Wicrk Me
Workholic0204
Threema
2kh7EXW5
Shipping Time
5 to 15 Days Before You Can Get Package After Pay
Shipping Company
UPS, DHL, FedEx and Others Based on Which Country
Shelf Life
48 Months
MOQ
100g
in Stock or Not
in Stock
Trademark
MSK
Transport Package
Discreet Packaging for Safety
Specification
1kg per Foil Bag
Origin
China
Model NO.
MSK55654654
Packaging
We Can Do Sub-Packaging Per Client′s Requirement
Delivery Promise
Reship Policy to Guarantee The Delivery Safety
Wicrk Me
Workholic0204
Threema
2kh7EXW5
Shipping Time
5 to 15 Days Before You Can Get Package After Pay
Shipping Company
UPS, DHL, FedEx and Others Based on Which Country
Shelf Life
48 Months
MOQ
100g
in Stock or Not
in Stock
Trademark
MSK
Transport Package
Discreet Packaging for Safety
Specification
1kg per Foil Bag
Origin
China
1. name: gw-0742
2. other name: gw610742
3. cas: 317318-84-6
4. molecular formula:c21h17f4no3s2
5. formula weight:471.5
6. appearance:white solid
7. mp:134.5-135.5 °c
8.category:sam steroid


gw0742
1. gw0742 is a high affinity ppar-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice.

2. a high throughput screening campaign was conducted to identify small molecules with the ability to inhibit
3. the interaction between the vitamin d receptor (vdr) and steroid receptor coactivator.

4. these inhibitors represent novel molecular probes to modulate gene regulation mediated by vdr. the peroxisome proliferator-activated receptor δ (pparδ) agonist gw0742 was among the identified vdr-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µm.

5. the highest antagonist activity for gw0742 was found for vdr and the androgen receptor (ar). surprisingly, gw0742 behaved as ppar agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations.

6. a unique spectroscopic property of gw0742 was identified as well. in the presence of rhodamine-derived molecules, gw0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner.

7. the gw0742-inhibited nr-coactivator binding resulted in a reduced expression of five different nr target genes in lncap cells in the presence of agonist. especially vdr target genes cyp24a1, igfbp-3 and trpv6 were negatively regulated by gw0742.

8. gw0742 is the first vdr ligand inhibitor lacking the secosteroid structure of vdr ligand antagonists. nevertheless, the vdr-meditated downstream process of cell differentiation was antagonized by gw0742 in hl-60 cells that were pretreated with the endogenous vdr agonist 1,25-dihydroxyvitamin d3.

Usage
1.the first and most common use is that of increased endurance. gw0742 has been banned for professional athletes due to the unfair advantage it provides to endurance athletes. anyone want a drastic increase in endurance will find that gw truly shines in this aspect. it takes effect very quickly and the results can be staggering. a common dose of 10 mg day will provide a significant increase in endurance.
2.the second common usage with gw0742 is that of fat loss. many users turn to gw as it has shown to melt off fat while still being non-catabolic. you will find that you can still hold on to some muscle as you are losing fat. it helps when you are running it in conjunction with sams ostarin and s4, to hold on to as much muscle as possible. a dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.



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1. All inquiry should be replied within 12 hours.

2. Faster delivery would be arranged within 24hours after payment from our clients.

3. Sample is available for your evaluation & Formulation development.

4. Quality is life of our buisness and long-termed business makes us place much emphasis on our products quality. And we must check the quality of every batch of products beforte sending out to clients .

5.After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.

6. We need to be familiar with your Country Customs, which can decrease your trouble, let's take some examples:

Δ Poland: When you send a parcel with total weight over 2kg they are going with different service and are checked more thorough .

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