Minoxidil is clinically used as a potassium channel opener, which can directly relax vascular smooth muscles and has a strong arterial expansion effect, which reduces peripheral resistance and blood pressure, but has no effect on volume vessels, so it can promote venous return. At the same time, due to the effect of reflex regulation and positive frequency, cardiac output and heart rate can be increased, but it does not cause orthostatic hypotension.

1. Minoxidil is the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). It is used to treat high blood pressure including hair growth and male alopecia.
2. Minoxidil can be used for refractory hypertension and renal hypertension
3. Minoxidil is a vasodilator and antihypertensive drug, which opens the K + channel, so that the vascular smooth muscle does not cause orthostatic hypotension and has no long-term drug efficacy.

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