White Freeze -Dried Powder Growth-Inhibiting Hormone Eptifibatide Integrilin 188627-80-7
China White Freeze-Dried Powder Growth-Inhibiting Hormone Eptifibatide Integrilin 188627-80-7, Find details about China 188627-80-7, Eptifibatide from White Freeze-Dried Powder Growth-Inhibiting Hormone Eptifibatide Integrilin 188627-80-7
Basic Info.
Model NO.
Eptifibatide
CAS
188627-80-7
Appearance
White Freeze-Dried Powder
Storage
Room Temperature Away From Light
Shelf Life
24month
Deliver Time
7-10 Days
Trademark
Biocar
Transport Package
10vials/Kit
Specification
1gram 10gram 1kg
Origin
Guangzhou China
HS Code
2935900090
Model NO.
Eptifibatide
CAS
188627-80-7
Appearance
White Freeze-Dried Powder
Storage
Room Temperature Away From Light
Shelf Life
24month
Deliver Time
7-10 Days
Trademark
Biocar
Transport Package
10vials/Kit
Specification
1gram 10gram 1kg
Origin
Guangzhou China
HS Code
2935900090
Product Desciption
White Freeze-Dried Powder Growth-Inhibiting Hormone Eptifibatide Integrilin 188627-80-7
Detailed Product Information
Product Name : Eptifibatide
Trade Name: integrilin
CAS No.:188627-80-7
Molecular Formula: C35H49N11O9S2
Molecular Weight:831.96g/mol
Purity : 98% HPLC
Appearance: Lyophilized Powder
Typical use:Anticoagulants
Shelf Life :2 years
Payment Terms:T/T, Western Union, Money Gram
Storage:Refrigeration keep dry and away from light.
Detailed Product Information
Product Name : Eptifibatide
Trade Name: integrilin
CAS No.:188627-80-7
Molecular Formula: C35H49N11O9S2
Molecular Weight:831.96g/mol
Purity : 98% HPLC
Appearance: Lyophilized Powder
Typical use:Anticoagulants
Shelf Life :2 years
Payment Terms:T/T, Western Union, Money Gram
Storage:Refrigeration keep dry and away from light.
Description:
Eptifibatide is a platelet glycoprotein b/a receptor reversible antagonist,adverse reactions are mild , it can be discontinued immediately while adverse reactions occur . It has Strong effect and high selectivity . It has no antigenicity,and it does not cause allergic reactions. It is used For acute coronary syndrome, coronary intervention before treatment and acute Q-wave myocardial infarction. It can relieve unstable angina symptoms and reduce the incidence of cardiovascular events. It can limit the non-Q-wave myocardial infarction,and reduce through wall myocardial infarction occurrance.
Application:
Etibatide is a glycoprotein (GP) IIb/IIIa receptor (platelet factor I receptor) antagonist. By selectively and reversibly inhibiting the final common pathway of platelet aggregation (plasma coagulation factor I binds to GPIIb/IIIa), the ischemic state due to thrombosis can be reversed.
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodi should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.
COA
Eptifibatide is a platelet glycoprotein b/a receptor reversible antagonist,adverse reactions are mild , it can be discontinued immediately while adverse reactions occur . It has Strong effect and high selectivity . It has no antigenicity,and it does not cause allergic reactions. It is used For acute coronary syndrome, coronary intervention before treatment and acute Q-wave myocardial infarction. It can relieve unstable angina symptoms and reduce the incidence of cardiovascular events. It can limit the non-Q-wave myocardial infarction,and reduce through wall myocardial infarction occurrance.
Application:
Etibatide is a glycoprotein (GP) IIb/IIIa receptor (platelet factor I receptor) antagonist. By selectively and reversibly inhibiting the final common pathway of platelet aggregation (plasma coagulation factor I binds to GPIIb/IIIa), the ischemic state due to thrombosis can be reversed.
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodi should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.
COA
| Item | Standard | Test Results |
| Identification | A.H-NMR:Comply with the structure | Complies |
| B.LC-MS:Comply with the structure | Complies | |
| C.The IR spectrum of sample should be identical with that of reference standard; | Complies | |
| D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Complies | |
| Crystallinity | meets the requirements. | Complies |
| Loss on drying | ≤2.0% | 0.19% |
| Heavy metals | ≤10 ppm | <10ppm |
| Water | ≤1.0% | 0.1% |
| Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% |
| Related substances | Unspecified impurities: for each impurity | <0.10% |
| Total Impurity | 0.18% | |
| Purity | ≥99.0% | 99.7% |
| Assay | 99.0%~101.0% (anhydrous substance). | 99.8% |
| Microbiological Analysis | ||
| Total plate count | ≤1000cfu/g | Complies |
| Yeast and Moulds | ≤100cfu/g | Complies |
| E. Coli. | Absent | Negative |
| Salmonella | Absent | Negative |
| S.aureus | Absent | Negative |
| Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies |
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