China High Quality Used Tablets Ivermectin CAS 70288-86-7 for Human Only, Find details about China 70288-86-7, Chemical from High Quality Used Tablets Ivermectin CAS 70288-86-7 for Human Only
Name : Ivermectin
Shape : White powder
This product is a derivative of abamectin, belongs to the oral semisynthetic broad-spectrum antiparasitic drug.It acts on most (but not all) nematodes of all life cycles;It is effective to the microfilariae of Orychonda, but not to the adults.It is also effective against Strongostrongylus faecalis, which lives only in the gut.This product has a selective inhibitory effect, by combining with the high affinity of the chloride ion channel of glutamate as the valve in the nerve cells and muscle cells of nonspinal animals, resulting in the increase of the permeability of the membrane to the chloride ion, causing the hyperpolarization of nerve cells or muscle cells, paralyzing or killing parasites.It also interacts with chloride channels of other ligand valves, such as the neurotransmitter G-aminobutyric acid (GABA).The selectivity of this product is due to the absence of glutamate chloride channels in some mammals and the fact that abamectin has only a low affinity for the mammalian ligand-chloride channel.This product does not penetrate the human blood-brain barrier.Onchocerciasis, Strongyliasis and hookworm, roundworm, whipworm and pinworm infections .
Ivermectin is a new type of broad-spectrum, high efficiency and low toxicity antibiotic against parasites, especially nematodes and arthropods.But not for tapeworms, flukes and protozoa.Large ring lactone class parasite drug resistance to nematodes and the function of flooding killed by arthropods, is to increase the insect body inhibitory neurotransmitter gamma aminobutyric acid (GABA) release, and open the glutamic acid control Cl ion channels, strengthen the nerve membrane permeability of Cl, thereby blocking nerve signal transmission, nerve palsy, eventually lose muscle contraction ability, thus killing the insect body .