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Focusherb Punica Granatum Extract 99% Urolithin a

China Focusherb Punica Granatum Extract 99% Urolithin a, Find details about China Urolithin a, 99% Urolithin a from Focusherb Punica Granatum Extract 99% Urolithin a

Model NO.
FHSP394
Product Name
Urolithin a
CAS
1143-70-0
Molecular Formula
C13h8o4
Molecular Weight
228.20
Sample
Provide
Solubility
Slightly Soluble in Ethanol, and Hardly Soluble in
Benefits
Anti-Aging, Improve Muscular Strength
Grade
Sports Nutrition, Dietary Supplements, Cosmetics
Trademark
FocusHerb
Transport Package
25kgs/Drum or Carton, Inner by Aluminum Foil Bag
Specification
99%
Origin
Shaanxi, China
Model NO.
FHSP394
Product Name
Urolithin a
CAS
1143-70-0
Molecular Formula
C13h8o4
Molecular Weight
228.20
Sample
Provide
Solubility
Slightly Soluble in Ethanol, and Hardly Soluble in
Benefits
Anti-Aging, Improve Muscular Strength
Grade
Sports Nutrition, Dietary Supplements, Cosmetics
Trademark
FocusHerb
Transport Package
25kgs/Drum or Carton, Inner by Aluminum Foil Bag
Specification
99%
Origin
Shaanxi, China
FocusHerb Punica Granatum Extract 99% Urolithin A
Focusherb Punica Granatum Extract 99% Urolithin a
What's Urolithin A Powder?
Urolithin A, Urolithin A is a naturally occurring metabolite generated by the human gut bacteria when you consume foods or supplements containing ellagitannins or ellagic acid.
Urolithin A 99%, with CAS number as 1143-70-0, is a beige to yellow powder for anti-aging and muscular strength.
Urolithin A Food Sources:
According to Wikipedia, Urolithin A is not known to be found in any dietary food source at present. However, you are able to get endogenously Urolithin A by digesting ellagitannins and ellagic acid-rich foods, which are dietary polyphenols found in various fruits and berries, nuts, muscadine grapes, oak-aged wines and spirits, such as pomegranates, blackberries, camu-camu, strawberries, raspberries, walnuts, hazelnuts, acorns, chestnuts, and pecans, etc.
Urolithin B VS Urolithin A:
Both Urolithin B and Urolithin A powder are used in supplements, but with different functional benefits. They work with a different mechanism of action. Urolithin A is mainly for the Anti-aging formula for its mitophagy mechanism while urolithin B is in sports nutrition formula as a muscle-building ingredient.
Urolithin A is a much more well-researched compound, it has been generally regarded as safe (GRAS) by the , while urolithin B is not. There are more supplement brands using urolithin A than urolithin B.
Urolithin A and Urolithin B are closed related. Pomegranate extract contains both of these urolithins. Pomegranates are the zenith of fruit. After digestion, their constituent parts can be converted by gut flora into urolithin C and then further transformed into Urolithin D and A, and then Urolithin B. In this sense, urolithin A can be converted to urolithin B.
Consequently, small amounts of urolithin B can be found in the blood of individuals fed with pomegranate extract; however, its antioxidant and anti-inflammatory properties are much weaker than urolithins A.
However, urolithin B has its own advantage over urolithin A. It's able to increase muscle cell size and accelerate muscle growth.

Focusherb Punica Granatum Extract 99% Urolithin aSynthetic Urolithin A VS Natural Urolithin A
As mentioned above, Urolithin A is a gut‐derived bacterial metabolite of ellagitannins(ET) or ellagic acid (EA). If you want to obtain a large quantity of Urolithin A, you have to first eat bulky fruits, and then wait for them to transfer from ellagitannins and ellagic acid to Urolithin A. This process is long, and its purity is low, and most importantly, it will be extremely expensive to do so.
Not everyone has the right microflora that can make the metabolite. In addition, this process can never be applied to mass production in a GMP-compliant manufacturing facility.
The good news is that, as a novel ingredient, Urolithin A is finally commercially available in 2019 from Cima Science. It now can be synthesized in the lab and factory. The synthetic urolithin A is identical in structure to natural urolithin A. The manufacturing capability is up to 2000 kgs or 2 tons/month.
Micronized Urolithin A:
The purity of urolithin A is 99% min tested by HPLC Method. Except for regular Urolithin A specification, Micronized Urolithin A powder is also available and carefully designed upon our nutritional supplement brands' request to provide a better bioavailability.
The specs of the particle size dimensions of micronized Urolithin A are NMT 30um and NMT 20um. And the actual batches are ranging
from 3um to 13um. It can be highly customized as per your detailed request.
Focusherb Punica Granatum Extract 99% Urolithin a
Focusherb Punica Granatum Extract 99% Urolithin a
Product NameUrolithin A
SourcePomegranate peels
CAS1143-70-0
Molecular FormulaC13H8O4
AppearanceBeige to Yellow powder
Specification99% byHPLC
Focusherb Punica Granatum Extract 99% Urolithin a
Urolithin A mechanism of action:
How does Urolithin A work? Ellagic acids and Ellagitannins are Urolithin A precursors.
Ellagitannins are hydrolyzed from the intestine into release Ellagic acid, and this is processed from the gut microflora to urolithins through the increasing loss in 1 of its two lactones successive removal of hydroxyl groups. Once It's consumed in the intestines, then Urolithin A powder enters the flow System of this intestine.
Mitophagy, according to Wikipedia definition, is the selective degradation of your mitochondria by autophagy. It often occurs to defective mitochondria following damage or stress. However, as we age, Mitophagy function becomes less efficient. Luckily,
Urolithin A is approved to stimulate mitophagy in a conserved manner across different species.
 
Urolithin A Benefits:
Human clinical trials show that Urolithin A supplementation is especially beneficial to anti-aging and muscular strength improvement. It may slow down a part of the aging process that's related to the creation of energy within our cells.
Muscle wellness undergoes a natural drop when you are 30+. Skeletal muscle mass declines along with a reduction in strength. Urolithin A enhances adrenal and muscular function, supplying more energy. It's a naturally-occurring anti-aging chemical that may benefit anyone seeking to maintain muscle health.
500mg Urolithin A was proven to cause gene expression linked to mitochondrial metabolism and function and boost the potency of the
hamstring leg muscle in steps of knee extension and flexion in obese 40 to 65-year-olds. Information from two randomized double-blind human clinical trials.
Where to buy Urolithin A bulk powder
FocusHerb is the leading manufacturer and supplier of natural ingredients. Pure urolithin powder and bulk urolithin A powder are both available. If you want to buy Urolithin B powder with purity up to 99%, please don't hesitate to leave a message below to get a quote immediately. Technical documents such as certificate of analysis (COA), MSDS (Material Safety Data Sheet), specification sheet, Method of Analysis (MOA), etc. are obtainable upon your specific request.
Focusherb Punica Granatum Extract 99% Urolithin aFocusherb Punica Granatum Extract 99% Urolithin aFocusherb Punica Granatum Extract 99% Urolithin a
Focusherb Punica Granatum Extract 99% Urolithin aFocusherb Punica Granatum Extract 99% Urolithin aFocusherb Punica Granatum Extract 99% Urolithin aFocusherb Punica Granatum Extract 99% Urolithin a
Q1: Are you manufacturer or trading company?
A1: We are manufacturer.
For some special or rare products, we can also make trade for you.

Q2: What certificate does your company have? 
A3: ISO 9001, Kosher, Halal, EU and USDA certificate are available.

Q3: Is the price on Ali page the final price?
A3: Not really. Some prices change from time to time and haven't been updated.
The actual price is subject to the salesman's quotation.

Q4: Can I get some sample?
A4: Yes, for most low value products, usually 10-20g free sample can be provided.

Q5: What's your MoQ?
A5: Our MoQ is flexible, usually 1 kg-10 kg for trial order.

Q6: How to start orders or make payments?
A6: There are two ways for you to confirm order:
1,Proforma invoice with our company bank details will be sent to you once the order confirmed. Pls arrange payment by TT (wire transfer).
2,Trade assurance order will be drafted for you through Alibaba. Pls confirm and pay through Alibaba (credit card).

Q7: How long for production and delivery?
A7: Most products we have in stock, lead time: within 1-4 business days after received payment.
Customized products further discussed.

Q8: What are your delivery methods?
A8: Fedex, DHL, By Air, By Sea and the specific line forwarder.
Recommend:
≤50kg by DHL/Fedex door to door, it will takes 5-7 days generally.
≤200kg by Air with airport to airport, it will takes 7-9 days generally.
≥200kg by Sea with port to port, it will takes 18-25 days generally.

Q9: How about the packing?
A9: 1 kg per aluminum foil bag, 20kg per carton, 25kg per drum and OEM package.

Q10: Do you accept ODM or OEM service?
A10: Sure, we make ODM and OEM services for many customers.
Ranges: Soft gel, Capsules, Tablets, Sachet, Granule, Private Label service, etc. Please contact us to design your own brand product.

Q11: What is the shelf life for the products?
A11: Most products shelf life 24-36 months, meet with COA.

Q12: Is there a discount?
A12: Of course, welcome to contact us. Price would be different based on different quantity. For bulk quantity, we will have discount for you.

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