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What is PQQ?

PQQ is a micronutrient that acts as an antioxidant in your body, protecting your cells (and specifically your mitochondria) from damaging free radicals. Most of the research around it has to do with mitochondrial density and function, which is why I found it so fascinating when I started researching supplements years ago. The more mitochondria you have and the better they function, the more energy and longevity you can expect.

You can find PQQ naturally in many foods, but not in super high amounts. It's especially high in green tea, fermented soy (natto), spinach parsely, and green peppers.^[1] However, the more I learn about PQQ supplementation, the more I suggest taking it in higher amounts than you can find in a salad.

 

Function of Pyrroloquinoline Quinone

PQQ and Your Mitochondria

Mitochondria are the tiny organelles working to produce cellular ATP, or adenosine triphosphate, the energy currency of your cells. All the energy in your body - your movements, your breath, and your thoughts - ultimately come from mitochondria. Mitochondria are in every cell in your body, but mitochondrial density is greatest in the areas of your body that require the most energy, like your brain and your heart. That's why a lot of the science around PQQ is for brain and heart function. And it's showing some really promising results.

Mitochondrial dysfunction, on the other hand, is one of the main biomarkers of aging and disease. In fact, researchers can link mitochondrial dysfunction with nearly every disease associated with aging, from Alzheimer's to heart failure. The good news is, you can make your mitochondria stronger.

My own mitochondrial function has been a focus of biohacking for years. A huge number of the things I do have a direct impact on how mitochondria work. Things like ketosis, Brain Octane Oil, high-intensity exercise, Bulletproof intermittent fasting, and avoiding the toxins that make you weak all help strengthen your mitochondria and create new ones.

If you find a way to improve your mitochondrial function, you'll make energy more efficiently. One of the most exciting ways I've found of increasing mitochondrial function is the compound pyrroloquinoline quinone.

The Benefits of PQQ

There is a lot of research (note that most of these studies are in rats) supporting PQQ's ability to kick your mitochondria into high gear. Specifically, research shows it can:

• Increase mitochondrial density to give you more energy
• Reduce inflammation
• Boost metabolism
• Combat oxidative stress
• Improve fertility
• Improve learning and memory ability
• Protect your heart

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