Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cellcytokines. It has been shown to influence the concentration of monoamine neurotransmitters[2] and induce metabolism of serotonin. Selank has also been found to rapidly elevate the expression of brain-derived neurotropic factor (BDNF) in the hippocampus of rats.

Selank, as well as a related peptide drug, Semax, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides, and this action may be involved in their effects. It has also been found to affect the activity of carboxypeptidase H and phenylmethylsulfonylfluoride-inhibitedcarboxypeptidase in rat nervous system tissue.

Selank has been found to produce antidepressant-like effects in animal models of depression and anhedonia.

Clinical trials
In clinical trials, the drug has shown to provide a sustained nootropic and anxiolytic effect which is useful for the treatment of generalized anxiety disorder (GAD).Selank has an advantage over traditional anxiety treatments as it has no sedating or negative cognitive side effects and no associatedaddiction or withdrawal problems.

Selank is closely related to another nootropic drug, Semax, also developed by the Institute of Molecular Genetics in Russia. This drug is currently available in Russian and Ukrainian pharmacies.As with all lipophilized peptides, it needs refrigeration to remain stable within sterile water solutions, such as bacteriostatic water concentrations.

Selank is used to improve one's ability to focus and concentrate, reduce mental fatigue, increase mental sharpness and increase memory and learning capacity. The first noticeable effect is usually stabilization of mood and general feeling of well-being.

Selank oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements. 

Selank peptide is an indole alkaloid derived from the bark of the Central African selank  tree that is widely used as an herbal therapy for erectile dysfunction.