Supply Veterinary API Powder CAS 1397 -89-3 Amphotericin B

China Supply Veterinary API Powder CAS 1397-89-3 Amphotericin B, Find details about China Amphotericin B, 1397-89-3 from Supply Veterinary API Powder CAS 1397-89-3 Amphotericin B

Basic Info.

Model NO.

TY-02AL

CAS No.

1397-89-3

Appearance

White Powder

Einecs

616-396-9

Assay

99%

Shelf

2 Years

Trademark

tongyon

Transport Package

25kg/Drum 1g,10g,100g,500g,1kg, 10kg, 100kg, 200kg

Specification

25kg/drum

Origin

China

Model NO.

TY-02AL

CAS No.

1397-89-3

Appearance

White Powder

Einecs

616-396-9

Assay

99%

Shelf

2 Years

Trademark

tongyon

Transport Package

25kg/Drum 1g,10g,100g,500g,1kg, 10kg, 100kg, 200kg

Specification

25kg/drum

Origin

China

Product Desciption

Product name	Amphotericin B
CAS	1397-89-3
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Amphotericin B
CAS:1397-89-3
MF:C47H73NO17
MW:924.08
EINECS:215-742-2
Mol File:1397-89-3.mol
Melting point:>170°C
alpha D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Boiling point:804.34°C (rough estimate)
Density 1.34
refractive index 1.5280 (estimate)
storage temp. 2-8°C
solubility sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20?#x00b0;C. Stable at 37?#x00b0;C for 3 days.
pkapKa ~5.7(DMF/H2O) (Uncertain)
form powder
color yellow
Water Solubility <0.1 g/100 mL at 21 ºC

Supply Veterinary API Powder CAS 1397-89-3 Amphotericin B

Description
Amphotericin B is a polyene macrolide antibiotic which was introduced into clinical medicine in 1955. It is primarily used for the treatment of serious systemic fungal infections. It is also used as an alternative drug for the treatment of drug resistant Leishmania. Amphotericin B is an effective drug, but its use is limited because of its toxicity. The advent of liposome encapsulated amphotericin may increase its use in multiresistant Leishmania in the future[1].
The mechanism of action of amphotericin is as yet not clear. In mycosis it binds to ergosterol present in fungal cell membranes. As a result, the drug forms pores or channels on the cell membrane which disturbs the membrane function allowing electrolytes (particularly potassium) and small molecules to leak from the cell resulting in cell death [2]. Oxidative damage to the cell may also be involved in this process [3]. Its mechanism of action in leishmaniasis may be similar to that in fungi.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company phiosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Supply Veterinary API Powder CAS 1397-89-3 Amphotericin B