China Pharmaceutical Chlorphenamine Maleate Antihistamine Chlorphenamine Maleate Powder Purity Chlorphenamine Maleate, Find details about China Chlorphenamine Maleate, Pharmaceutical Chlorphenamine Maleate from Pharmaceutical Chlorphenamine Maleate Antihistamine Chlorphenamine Maleate Powder Purity Chlorphenamine Maleate
product Name | Chlorpheniramine Maleate |
Other Name | Chlorphenamine |
CAS No. | 113-92-8 |
Einecs No. | 204-037-5 |
Appearance | White powder |
Speccification | 99% |
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemiareperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.