Dexametha Sone CAS 50-02-2 API Raw Material White Power Pharmaceutical Chemical
China Dexametha Sone CAS 50-02-2 API Raw Material White Power Pharmaceutical Chemical, Find details about China CAS 50-02-2, Dexametha Sone from Dexametha Sone CAS 50-02-2 API Raw Material White Power Pharmaceutical Chemical
Basic Info.
Model NO.
CAS 50-02-2
Appearance
White, Crystalline Powder
Transport Package
25kg/Carton
Origin
China
HS Code
2937221000
Model NO.
CAS 50-02-2
Appearance
White, Crystalline Powder
Transport Package
25kg/Carton
Origin
China
HS Code
2937221000
Product Desciption
DEXAMETHA SONE CAS 50-02-2 API Raw Material White Power
Introduction:
Dexametha sone is an Anti-inflammatory glucocorticoid that is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide.Dexametha sone induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitriccoxide synthase (IC50=5 nM). Dexametha sone has been shown to cause reduction in cyclin A and Cd k2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro. Dexametha sone has been observed to induce apoptosis in human thymocytes and eosinophils, but inhibits apoptosis in neutrophils in vitro. Dexametha sone is an activator of IDO.Dexametha sone Inhibits the expression of the inducible but not the constitutive nitriccoxide synthase in vascular endothelial cells (IC50=5 nM). Dexametha sone regulates T cell survival, growth, and differentiation.Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexametha sone is sufficient to induce apoptosis following a 6-hour incubation at 37°C.
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Dexametha sone is an Anti-inflammatory glucocorticoid that is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide.Dexametha sone induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitriccoxide synthase (IC50=5 nM). Dexametha sone has been shown to cause reduction in cyclin A and Cd k2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein in vitro. Dexametha sone has been observed to induce apoptosis in human thymocytes and eosinophils, but inhibits apoptosis in neutrophils in vitro. Dexametha sone is an activator of IDO.Dexametha sone Inhibits the expression of the inducible but not the constitutive nitriccoxide synthase in vascular endothelial cells (IC50=5 nM). Dexametha sone regulates T cell survival, growth, and differentiation.Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexametha sone is sufficient to induce apoptosis following a 6-hour incubation at 37°C.
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