Anti -Mapre1/Eb1 Rabbit Primary Antibody

China Anti -Mapre1/Eb1 Rabbit Primary Antibody, Find details about China Mapre1/Eb1, Mapre1 Antibody from Anti -Mapre1/Eb1 Rabbit Primary Antibody

Basic Info.

Model NO.

GB111069

Trademark

Servicebio/customized

Origin

Hubei

HS Code

3502900000

Model NO.

GB111069

Trademark

Servicebio/customized

Origin

Hubei

HS Code

3502900000

Product Desciption

Anti -MAPRE1/EB1Rabbit Primary Antibody

Product Information

Description	EB1 rabbit polyclonal
Protein full name	Microtubule-associated protein RP/EB family member 1
Synonyms	APC-binding protein EB1, End-binding protein 1, EB1, Mapre1
Immunogen	Recombinant protein corresponding to Mouse EB1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	30 kDa
Observed MW.	30-35 kDa
Uniprot ID	Q61166

Applications

Applications	WB
Species	Human, Mouse
Dilution	1: 500-1: 1000
Positive tissue	colon, thymus

Background

The EB1 protein Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules. Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (By similarity). May play a role in cell migration.

Images

Western blot analysis of EB1 (GB111069) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: 293T cell lysate
Lane 3: Mouse colon tissue lysate
Lane 4: Mouse thymus tissue lysate

Storage

Storage	Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

Anti -Mapre1/Eb1 Rabbit Primary Antibody