Anti -Clip170 Rabbit Primary Antibody

China Anti -Clip170 Rabbit Primary Antibody, Find details about China Antibody, Primary Antibody from Anti -Clip170 Rabbit Primary Antibody

Basic Info.

Model NO.

GB111068

Trademark

Servicebio

Origin

China

HS Code

3502900000

Model NO.

GB111068

Trademark

Servicebio

Origin

China

HS Code

3502900000

Product Desciption

Anti -CLIP170 Rabbit Primary Antibody

Product Information

Description	CLIP170 rabbit polyclonal
Protein full name	CAP-Gly domain-containing linker protein 1
Synonyms	Cytoplasmic linker protein 170, CLIP-170, Restin, Clip1, Kiaa4046, Rsn
Immunogen	Recombinant protein corresponding to Mouse CLIP170
Isotype	IgG
Purity	Affinity purification
Predicted MW.	156 kDa
Observed MW.	170-200 kDa
Uniprot ID	P30622, Q922J3, Q9JK25

Applications

Applications	WB
Species	Human, Mouse, Rat
Dilution	1: 500-1: 1000
Positive tissue	brain

Background

CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1.

Images

Western blot analysis of CLIP170 (GB111068) at dilution of 1: 1000

Lane 1: Hela cell lysate
Lane 2: 293T cell lysate
Lane 3: MCF7 cell lysate
Lane 4: Mouse brain tissue lysate
Lane 5: Rat brain tissue lysate

Storage

Storage	Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

Anti -Clip170 Rabbit Primary Antibody