Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody

China Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody, Find details about China for Research Only, Liquid from Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody

Model NO.
GB111054
HS Code
3502900000
Model NO.
GB111054
HS Code
3502900000
Product Description

 

 

Anti -KMT1B / SUV39H2 Rabbit Primary Polyclonal Antibody

 
Product Information
 

Description

SUV39H2 rabbit polyclonal

Protein full name

Histone-lysine N-methyltransferase SUV39H2

Synonyms

Histone H3-K9 methyltransferase 2, KMT1B, H3-K9-HMTase 2, Lysine N-methyltransferase 1B, Suppressor of variegation 3-9 homolog 2, Su(var)3-9 homolog 2, SUV39H2

Immunogen

Recombinant protein corresponding to Mouse SUV39H2


Isotype
 
IgG

Purity
 
Affinity purification
Subcellular location

Nucleus

Uniprot ID

Q9H5I1

 

Applications

Applications

IHC

IF

Species

Human

Human

Dilution

1: 1000-1: 2000

1: 500-1: 1000

Positive tissue

breast cancer

breast cancer

Background

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.

Images

Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody

Immunohistochemistry analysis of paraffin-embedded human breast cancer using SUV39H2 (GB111054) at dilution of 1: 2000



Storage
 

Storage
 
Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.

Storage Buffer
 
PBS with 0.02% sodium-azide, 100 μg/ml BSA and 50% glycerol. 
 
 
Certifications

Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal AntibodyAnti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody

Company Profile

Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal AntibodyAnti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody

FAQ

Anti -Kmt1b / SUV39h2 Rabbit Primary Polyclonal Antibody