Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus
China Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus, Find details about China Tacrolimus, Powder Tacrolimus from Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus
Basic Info.
Model NO.
D-sung Tacrolimus
Product Name
Tacrolimus
Name
Tacrolimus Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Immunosuppressive
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
104987-11-3
Mf
C44h69no12
MW
804.031
Boiling Point
871.7 °c at 760 Mmhg
Density
1.19
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Tacrolimus
Product Name
Tacrolimus
Name
Tacrolimus Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Immunosuppressive
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
104987-11-3
Mf
C44h69no12
MW
804.031
Boiling Point
871.7 °c at 760 Mmhg
Density
1.19
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Raw Materials CAS 104987-11-3 Tacrolimus Purity Tacrolimus Powder Pharmaceutical Tacrolimus
| Product name | Tacrolimus |
| Cas number | 104987-11-3 |
| Appearance | White powder |
| MF | C44H69NO12 |
| MW | 804.031 |
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
1. Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant.
2. Tacrolimus is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
3. Tacrolimus can be combined with steroids, azathioprine (Imuran Azasan) or mycophenolate mofetil (CellCept.
1. Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant.2. Tacrolimus is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
3. Tacrolimus can be combined with steroids, azathioprine (Imuran Azasan) or mycophenolate mofetil (CellCept.
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