G'onadorelin
CAS No:33515-09-2
MF:C55H75N17O13
MW:1182.29
EINECS:251-553-1
Specification:2mg/vial,5mg/vial,10mg/vial.
Appearance:White frozen dry powder/lyophilized powder

G'onadorelin is indicated (approved) for the treatment of ovarian follicular cysts in dairy cattle. Additionally, g-onadorelin has been used in cattle to reduce the time interval from calving to first ovulation and to increase the number of ovulations within the first 3 months after calving. This may be particularly important in increasing fertility in cows with retained placenta.

In dogs, g-onadorelin has been used experimentally to help diagnose reproductive disorders or to identify intact animals versus castrated ones by maximally stimulating FS and L production. It has also been used experimentally in dogs to induce estrus through pulsatile dosing. While apparently effective, specialized administration equipment is required for this method.

G-onadorelin has been used in cats as an alternate therapy to FS or hC to induce estrus in cats with prolonged anestrus.

In Europe, a synthetic analogue b-userelin has been used in horses to stimulate cyclic estrus. Its efficacy rates poorly when compared to an artificial light program, however.

In human medicine, g-onadorelin has been used for the diagnosis of hypothalamic-pituitary dysfunction, cryptorchidism, and depression secondary to prolonged severe stress.