China 99.9% Purity Azaperone Powder with Safe Customs Clearance, Find details about China Azaperona, Azaperone Factory from 99.9% Purity Azaperone Powder with Safe Customs Clearance
Product Name: Azaperone
CAS: 1649-18-9
MF: C19H22FN3O
MW: 327.4
EINECS: 216-715-8
Chemical Properties Off-White Solid
Usage H1 antihistamine (nonsedating); leucotriene synthesis blocker
Usage Sedative; tranquilizer.
purity: 99%
Azaperone Description
Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. It is uncommonly used in humans as an antipsychotic drug .
Azaperone acts primarily as a dopamine antagonist but also has some antihistaminic and anticholinergic properties as seen with similar drugs such as haloperidol. Azaperone may cause hypotension and while it has minimal effects on respiration in pigs, high doses in humans can cause respiratory depression .
Veterinary use
The most common use for azaperone is in relatively small doses to reduce aggression in farmed pigs, either to stop them fighting or to encourage sows to accept piglets. Higher doses are used for anesthesia in combination with other drugs such as xylazine, . Azaperone is also used in combination with strong narcotics such as or for tranquilizing large animals such as elephants. Use in horses is avoided as adverse reactions may occur.
The European Medicines Agency has established a maximum residue limit for azaperone when administered to pigs.
Azaperone was approved for use in pigs in the USA in 1983, under NADA 115-732.
CERTIFICATE OF ANALYSIS:
Product name | Azaperone | |||
CAS No. | 1649-18-9 | Outer Packing | 1KG/BAG | |
Production date | 20170525 | Shelf life | 20190524 | |
Standard adopted | BP 2010 | |||
Items of analysis | Specification | Results | ||
Appearance | White or almost white powder | Meet the Requirements | ||
Solubility | Practically insoluble in water, freely soluble in and Methylene Chloride, soluble in Alcohol | Confirms | ||
Identification | IR | Positive | ||
Loss on drying | ≤0.5% | 0.26% | ||
Impurity A | ≤0.25% | 0.11% | ||
Total impurity B and C | ≤0.75% | 0.14% | ||
Total impurity | ≤1.0% | 0.40% | ||
Disregard Limit | ≤0.05% | 0.05% | ||
Appearance of solution | Clear solution | Confirms | ||
Sulphated ash | ≤0.1% | 0.08% | ||
Assay:(HPLC) | 99-101% | 99.8% | ||
Conclusion | Qualified |
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