China cosmetic Raw Material Poly-L-Glutamic Acid/Gamma-PGA with Best Price, Find details about China Poly Glutamic Acid, Pharma from cosmetic Raw Material Poly-L-Glutamic Acid/Gamma-PGA with Best Price
Poly Glutamic Acid / gamma-PGA Basic Info
Product Name | Gamma Poly Glutamic Acid |
CAS No. | 25513-46-6 |
Molecular Formula | L-Glu-(L-Glu)n-L-Glu |
Molecular Weight | N/A |
Appearance | White Powder |
Assay | 99% |
Grade | Cosmetic Grade |
Poly Glutamic Acid / gamma-PGA Descrption
Poly Glutamic Acid is a water soluble, biodegradable, non-toxic biopolymer produced by microbial fermentation.Poly Glutamic Acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid.
It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.
PGA is an unusual anionic, naturally occurring homo polyamide that is made of D & L glutamic acid units connected by amide linkages between alpha amino & gamma carboxylic acid groups.
Gamma-poly-glutamic acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 100~1000 kDa. It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.
Poly Glutamic Acid / gamma-PGA Application:
Effectively Increasing NMF in Inner Skin
As a hygroscopic material produced by skin, Natural Moisturizing Factor ( NMF ) provides moisture for skin in cuticle. The NMF including amino acids which are hydrolyzed on skin matrix protein ( e.g. Filament aggregating protein ), pyrrolidone carboxylic acid ( PCA ), lactic acid and urocanic acid ( UCA ) can retain moisture of skin. Gamma PGA is the only effective ingredient that is known till now to induce the production of NMF to 130% of the normal level. Gamma PGA can lock the moisture in inner skin by promoting the growth of fibroblast and increasing the content of NMF in horn cells.
Improving Nutrient Supply
Thanks to its controlled release property, gamma PGA can control the release of nutrients and moisture in a continuous manner. Each gamma PGA monomer has ionized groups likeα COOR, -CO and -NH, which can absorb electropositive nutrients. Hence a good embedding delivery system is created and active ingredients in cosmetics can possibly maximize their efficacy.
Healthy Whitening Efficacy
Gamma PGA can also whiten skin by controlling melanin synthesis to prevent and reduce wrinkle's. Ultraviolet irradiation is the main incentive of tyrosinase, which in tum induces the formation of Melanin. As gamma PGA, either HM gamma PGA ( 0.5% ) or LM gamma PGA ( 0.5% ) can effectively inhibit the formation of melanin. Meanwhile, gamma PGA can form a film upon surface of skin which fences out ultraviolet.
Applications of Gamma PGA in Skin - care Products
Gamma PGA has excellent compatibility in non-ionic, anionic and amphoteric surfactants. It is a perfect ingredient for cream, essence, astringent, face mask, eye gel, sun cream, shampoo, body wash, lotion, hairstyle formula and so on.