Product Basic Information:Common Name | Amphotericin B |
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CAS Number | 1397-89-3 |
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Amphotericin B Density | 1.3±0.1 g/cm3 |
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Amphotericin B Boiling Point | 1140.4±65.0 °C at 760 mmHg |
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Amphotericin B Melting Point | >170°C |
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Amphotericin B Molecular Formula | C47H73NO17 |
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Amphotericin B Molecular Weight | 924.079 |
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Amphotericin B Flash Point | 643.5±34.3 °C |
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Amphotericin B Exact Mass | 923.487854 |
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Amphotericin B PSA | 319.61000 |
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Amphotericin B LogP | 1.16 |
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Amphotericin B Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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Amphotericin B Index of Refraction | 1.614 |
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Amphotericin B Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
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Amphotericin B Water Solubility | sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20C. Stable at 37C for 3 days. | <0.1 g/100 mL at 21 ºC |
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Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For certain infections it is given with flucytosine. It is typically given by injection into a vein. Synonyms
Ampho-moronalLNS-AmBAmphocinAmphotecMFCD00877763HalizonFungilinEINECS 215-742-2AmphozoneAmphotericin BAmBisomeFUNGIZONEns718AbelcetAbelecet
1.What is amphotericin B used to treat?Amphotericin B is an antifungal medication that fights infections caused by fungus. Amphotericin B is used to treat serious, life-threatening fungal infections.2.Is amphotericin B an antibiotic?Amphotericin B is an antibiotic used as the "gold standard" in the treatment of life-threatening fungal infections.3.What fungal infections does amphotericin B treat?A systemic inflammatory response called sepsis due to an infection with fungus.leishmaniasis.Candidiasis fungal infection of the oropharynx.Urinary tract infection due to Candida albicans fungus.Candidiasis yeast infection that spreads throughout body.Common side effects include a reaction with fever, chills, and headaches soon after the medication is given, as well as kidney problems. Allergic symptoms including anaphylaxis may occur. Other serious side effects include low blood potassium and inflammation of the heart. It appears to be relatively safe in pregnancy.There is a lipid formulation that has a lower risk of side effects. It is in the polyene class of medications and works in part by interfering with the cell membrane of the fungus. 1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
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