Microcrystalline Cellulose Micro Crystalline Cellulose CAS 9004-34-6

Microcrystalline cellulose (MCC, Microcrystalline cellulose), the main component is a linear polysaccharide substance bound by β-1,4-glucoside bonds, which is natural cellulose hydrolyzed by dilute acid to the limit degree of polymerization ( LOOP) free-flowing very fine short rod-like or powder-like porous particles, composed of white, odorless, tasteless crystalline powder.
In general plant fibers, microcrystalline cellulose accounts for about 70%, and the other 30% is amorphous. Cellulose microcrystalline cellulose is widely used in pharmaceutical, cosmetics, food and other industries. Different particle size and water content have different characteristics and application ranges.

In the food industry, as a kind of edible fiber and an ideal health food additive, microcrystalline cellulose can maintain the stability of emulsification and foam, maintain the stability of high temperature, and improve the stability of liquids. It has won the United Nations Food and Agriculture Organization and World Health Organization. With the certification and approval of the Food Additives Joint Appraisal Committee to which the organization belongs, corresponding fiber products have also appeared, and are widely used in dairy products, frozen foods, meat products, etc.
Microcrystalline cellulose can be used as anticaking agent, emulsifier, dispersant, and binder. my country's "Hygienic Standards for the Use of Food Additives" (GB2760-2011) stipulates that it can be used for non-dairy powder and cream, with a maximum usage amount of 20g/kg; for ice cream, 40g/kg; high-fiber foods and bread, 20g/kg. Other reference for use: Use in ice cream can improve the overall emulsification effect, prevent the formation of ice slag, and improve the taste. Combined with carboxymethyl cellulose can increase the suspension of cocoa powder in milk beverages.

Filler: Fillers are mandatory for tablet manufacturing where the doses of drugs are very low. MCC can be used for all types of tablet making processes like direct compression, wet granulation, and dry procession.

Direct Compression: MCC is used as an excipient in direct compression. It has high dilution capacity and higher active ingredient carrier capacity. It has the potential to hold itself together even under direct compression. Another reason for its popularity is the low bulk density; it will lead to high dilution and packing density. It helps in producing tablets with better hardness levels and less fragile. It also provides superior white color and provides stability.

Wet granulation: As mentioned earlier it has insoluble properties at the same time it is hydrophilic. Hence, it is preferred choice for this manufacturing process. The benefit of using MCC is that can retain water, it further helps in uniform granulation. Case solidifying is a process saw in deficiently dried granules. Now and again, when the granules are dried at a high temperature, within the granules stay wet also; the surface appears to be dried. MCC is useful as it is less sensitive to wet mass, therefore, it does not get over wet, dries faster, you will find fewer case hardening and disintegrates quickly.

Roller Compaction: Roller compaction is a dry procedure including compaction of materials into strips that are at that point processed to produce a granulation. This granulation is then greased up and packed on a tablet machine. Usage of MCC in this manufacturing process improves in compaction, flow enhancement, and content uniformity.

Binder: To gain the appropriate mechanical strength and give volume to the smaller active ingredient dose, binders are very helpful. It affects the quality and appearance of the tablet. Considering the hydrophyllic water wicking qualities of MCC, it is widely used as a binder in the pharmaceutical industry.

Disintegrant: MCC is broadly utilized as a disintegrant in dry compressions also, wet granulation systems. It improves tranquilize disintegration by speeding tablet deterioration, gives the largest amount of breaking down power at low utilize levels, and uses double breaking down instruments of wicking and swelling for more quick breaking down.

Company Profile
Hefei JOYE Import & Export CO.,LTD is a import and export trade company established in 2011.Approved by the Chinese government set up trade enterprises.The Customs Registration code of the company is 3401961603.

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