China Hot Sale Dl Methionine /Dl Methionine Price S-Adenosyl Methionine /Same CAS: 97540-22-2, Find details about China Dl Methionine, Dl Methionine Price S-Adenosyl Methionine from Hot Sale Dl Methionine /Dl Methionine Price S-Adenosyl Methionine /Same CAS: 97540-22-2
Product name: SAMe(S-Adenosyl-L-methionine)
Other Name: S-Adenosyl-L-Methionine Dissufate P-Toluenesulfonate, S-Adenosyl-L-Methionine Disulfate
Tosylate
Appearance: light yellow to off-white
CAS No.: 97540-22-2
EINECS: 249-946-8
Molecular formula: C15H22N6O5S
Purity:99%
S-Adenosyl-L-methionine(SAMe) is a common cosubstrate involved in methyl group transfers. SAMe was first discovered in Italy by G. L. Cantoni in 1952, SAMe is a molecule produced constantly by all living cells,can preventing liver cancer, promoting cartilaginous tissue forming and concrescence, may help fight depression, alzheimer's disease, liver disease, and the pain of osteoarthritis,SAMe is now universerally acknowleged as an important pharmaceuticals to treat liver diseases. Nowaday SAMe is commonly used in pharmaceuticals, health care food industry both at domestic and international market.
(1) SAMe is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;
(2) SAMe has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on.
(3) SAMe has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.
(4)In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled SAME or SAMe). Some research has indicated that taking SAM on a regular basis help fight depression, liver disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet proven.
Test | Specifications | Result |
P-toluenesulfonatic acid: | 21.0%~24.0%(basis on dried) | 23.5% |
Sulfates: | 23.5%~26.5%(basis on dried) | 25.1% |
Ademtionine | ≥49.5% | 50.9% |
Total content: | ≥98% | 99.5% |
Appearance: | Almost white powder, hygroscopic | Complies |
Identification: | 1) Chemical reaction | Positive reaction |
2)IR: consistent with the spectrum obtained with reference Substance | Complies | |
3)HPLC: the retention time of a major peak meets the requirements. | Complies | |
Acid value: | 1.0-2.0 | 1.6 |
Clarity and color of solution: | Not more intensely colored than refrence solution Y2 | Complies |
Solubility: | Soluble in water | Complies |
Water: | ≤2.5% | 1.6% |
S-adenosyl-L-Homocystein: | ≤0.5% | 0.05% |
Methithioadenosine: | ≤2.0% | 0.23% |
Adenine: | ≤0.5% | 0.30% |
Related substance: | The sum area of unknown impurities must be not more than 1.5 times of reference solution main peak's (1.5%) | 0.14% |
(S, S)Isomer: | ≥60.0% | 77.6% |
Endotoxin: | ≤0.3EU/mg | Complies |
Heavy metals PPM: | N.M.T10ppm | Complies |
Microbiology: Total Plate Count: Yeast & Mold: E.Coli: S. Aureus: Salmonella: |
<1000cfu/g <100cfu/g Negative Negative Negative |
Complies Negative Complies Complies Complies |
Conclusion: | Conform with specification |