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Tranexamic acid is a synthetic derivative of the amino acid lysine.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule
responsible for the degradation of fibrin. Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid.

1.Menstrual bleeding
Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen
molecules.Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.
Tranexamic acid is used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.
2.Orthopedic Surgery
Tranexamic acid is used in orthopedic surgery to reduce bloodloss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.
3.Trauma
Tranexamic acid should be considered for use in bleeding trauma patients.

Cosmetics: Whitening effect Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%



 

 

 

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