China Pharmaceutical CAS 198470-85-8 Parecoxib Sodium, Find details about China Parecoxib Sodium, Top Quality Parecoxib Sodium from Pharmaceutical CAS 198470-85-8 Parecoxib Sodium
Product Name | Pharmaceutical CAS 198470-85-8 Parecoxib Sodium |
CAS | 198470-85-8 |
Appearance | White Powder |
Molecular formula | C19H17N2NaO4S |
Molecular Weight | 392.40405 |
Assay | 98% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Parecoxib sodium?Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications. It is approved through much of Europe for short term perioperative pain control much in the same way ketorolac(Toradol) is used in the United States. However, unlike ketorolac, parecoxib has no effect on platelet function and therefore does not promote bleeding during or after surgery. In addition, ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal antiinflammatory drugs (NSAIDs) including ibuprofen and naprosyn. However, in the United States ketorolac is the only injectable NSAID, although it is banned in many European countries due to concerns about surgical bleeding and stomach ulcers after surgery. |
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