Natural Extract Tetrahydropalmatine Rotundine Raw Material Powder

Product Name    Tetrahydropalmatine
Part Used    Rotundine
Appearance    White Powder
Active Ingredient    THP
Specification    99%

Tetrahydropalmatine (THP) is an alkaloid found in several different plant species,mainly in the Corydalis family, but also in other plants such as Stephania rotunda.These plants have traditional uses in Chinese herbal medicine.The pharmaceutical industry has synthetically produced the more potent enantiomerLevo-tetrahydropalmatine (Levo-THP),which has been marketed worldwide under different brand names as an alternative to anxiolytic and sedative drugs of the benzodiazepine group and analgesics such as opiates.It is also sold as a dietary supplement.
Tetrahydropalmatine has been demonstrated to possess analgesic effects and may be beneficial in the treatment of heart disease and liver damage. It is a blocker of voltage-activated L-type calcium channel active potasium channels.It is a potent muscle relaxant. It has also shown potential in thetreatment of drug addiction to both  and opiates,and preliminary human studies have shown promising results.
Animal experiments have shown that the sedative effect of THP results from blocking dopaminergic neurons in the brain.Dopamine is an important neurotransmitter in the central nervous system where it occurs in several

Function

1) It has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
2) It is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.

Application

1.Tetrahydropalmatine/Rotundine has the protective effect on liver injury induced by carbon tetrachloride in mice.
2.Tetrahydropalmatine/Rotundine has analgesia and sedative-hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain.
3.Tetrahydropalmatine/Rotundine has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.
4.Tetrahydropalmatine/Rotundine is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.