China GMP Factory Direct Supply 99% Purity Propitocaine Raw Powder CAS: 721-50-6, Find details about China Propitocaine, Propitocaine Powder from China GMP Factory Direct Supply 99% Purity Propitocaine Raw Powder CAS: 721-50-6
Procaine was first synthesized in 1905,shortly after amylocaine.It was created by the German chemist Alfred Einhorn who gave the chemical the trade name , from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics.It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of amylocaine and procaine, was the most commonly used local anesthetic. Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful. Einhorn was displeased by this and spent many years touring dental schools to advise them not to use it.
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren.In its injectable form (trade name Citanest), it is often used in dentistry.It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
Prilocaine topical is a local anesthetic (numbing medication).It works by blocking nerve signals in your body. Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine was first synthesized in 1905,shortly after amylocaine.It was created by the German chemist Alfred Einhorn who gave the chemical the trade name , from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics.It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of amylocaine and procaine, was the most commonly used local anesthetic. Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful. Einhorn was displeased by this and spent many years touring dental schools to advise them not to use it.
Items Tested | Specification | Result | |
Characters | White or almost white crystalline powder | Confirms | |
Melting Point | 166ºC-169ºC | 166.5ºC-168.5ºC | |
Solubility | Freely soluble in water and in alcohol | Confirms | |
Assay (HPLC) | 99.0--101.0% (calculated on the dried basis) | 99.6% | |
Loss on Drying | Not more than 0.3% | 0.16% | |
Related substances | Not more than 1.0% | 0.11% | |
Ace | Not more than 5000ppm | conforms | |
Ethanol | Not more than 5000ppm | conforms | |
Sulphated ash | Not more than 0.15% | conforms | |
Heavy Metal | Not more than 0.001% | <0.001% | |
Conclusion | Conforms USP36 |
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