Function

The most common side effect of sulfamethoxazole is gastrointestinal upset. Allergies to sulfa-based
medications typically cause skin rashes, hives, or trouble breathing or swallowing and warrant immediate
discontinuation of the medication and contact with doctor immediately. 

Sulfamethoxazole is also known to increase blood concentrations of the drug warfari
(U.S. brand name: Coumadin) and can cause an unexpected increase in clotting time and uncontrolled
bleeding. 


Neutropenia and thrombocytopenia also are rare adverse effects to be monitored if a patient is placed on
long-term therapy.

Sulfamethoxazole can also be used to treat toxoplasmosis.
Application

sulfamethoxazole is primary activity is against susceptible forms of Streptococcus, Staphylococcus aureus
(including MRSA), Escherichia coli, Haemophilus influenzae, and oral anaerobes.  sulfamethoxazole is
commonly used to treat urinary tract infections. In addition can be used as an alternative to amoxicillin-
based antibiotics to treat sinusitis.

Specification