The Hexapeptide-10 corresponds to residues 2099-2104 of the laminin α1 chain. Hexapeptide-10 has been shown to modulate tumor invasion, metastasis and angiogenesis. It also induced the synthesis of prostaglandin E2, interstitial collagenase, and gelatinase B in monocyte cell cultures. Laminin fragments containing the SIKVAV sequence may contribute to the inflammatory response at sites of wound healing. They may also play a role in the excessive induction of metalloproteinases in chronic inflammatory lesions.

Hexapeptide-10 is from an adhesion sequence of laminin, which restores the cutaneous structure.Hexapeptide-10 is a firming active that promotes a double-cellular activity on both keratinocytes and fibroblast. It increases the synthesis of laminin-5, alpha6-integrin and hemidesmosomes, thus strengthening the dermal-epidermal junction. With Hexapeptide-10,the skin is restructured, replenished, firmer and more elastic, recovering its fullness.

What are Peptides for Skin Care?

Science has proven that peptides can help manage wrinkles in your skin and reverse the signs of aging.Human skin is comprised mostly of collagen. Collagen is a protein comprised of long segments of amino acids arranged like a chain. Collagen provides a foundation and thickness for skin.Women under 30 have ample collagen, which results in smooth, tight skin.

The rest of us have less collagen - skin tends to be thinner, revealing more wrinkles.
When collagen breaks down, short segments of amino acids are formed. These are the tiny proteins and active molecules known as peptides. Peptides in skin care can provide significant anti-aging benefits.