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Levonorgestrel Tablets

China Levonorgestrel Tablets, Find details about China Levonorgestrel Tablets, Oral Contraceptive Pill from Levonorgestrel Tablets

Pharmaceutical Technology
Chemical Synthesis
Trademark
ELA LOVE
Specification
1.5mg
Origin
China
Pharmaceutical Technology
Chemical Synthesis
Trademark
ELA LOVE
Specification
1.5mg
Origin
China
COMPOSITION 
Each tablet contains 1.5 mg of  levonorgestrel. 

PHARMACOLOGICAL ACTION 
Pharmacodynamics 
The precise mode of action of levonorgestrel is not known. Emergency hormonal contraception is thought to work mainly by preventing fertilisation by altering tubal transport of sperm and/or ova. It may also cause endometrial changes that discourage implantation. 
Efficacy: It has been estimated that levonorgestrel prevents 84% of expected pregnancies. At the recommended regimen, levonorgestrel is not expected to induce significant modification of blood clotting factors, and lipid and carbohydrate metabolism. 
Pharmacokinetics 
Orally administered levonorgestrel is rapidly and almost completely absorbed. 
The results of a pharmacokinetic study carried out with 16 healthy women showed that following ingestion of one tablet of levonorgestrel, maximum drug serum level of 18,5 ng/mL was found at 2 hours. The mean value of area under the levonorgestrel concentration-time curve (0-infinity) was calculated as 310,2 ng.h/mL. After reaching maximum serum levels, concentration of levonorgestrel decreased with mean elimination half-life of about 26 hours. 

INDICATIONS 
Emergency contraception within 72 hours of unprotected sexual intercourse or failure of a contraceptive method. 
Take the first tablet as soon as possible within72hours(3 days) after unprotected sex.The sooner you take the first tablet, the better Levonorgestrel tablets,0.75 mg will work. take the second tablet 12 hours later.

CONTRA-INDICATIONS 
-Hypersensitivity to the active substance levonorgestrel or to any of the excipients.
-Severe hepatic insufficiency.
-Pregnancy or suspected pregnancy (see Pregnancy and Lactation).

WARNINGS 
Emergency contraception is an occasional method to be used in an "emergency situation" only. It should in no instance replace a regular contraceptive method. ESCAPELLE does not prevent a pregnancy in every instance. 
If there is uncertainty about the timing of the unprotected intercourse or if the woman has had unprotected intercourse more than 72 hours earlier in the same menstrual cycle, conception may have occurred. Treatment with ESCAPELLE following the second act of intercourse may therefore be ineffective in preventing pregnancy. If menstrual periods are delayed by more than 5 days or abnormal bleeding occurs at the expected date of menstrual periods or pregnancy is suspected for any other reason, pregnancy should be investigated. 

INTERACTIONS 
The metabolism of ESCAPELLE is enhanced by concomitant use of liver enzyme inducers. Medicines suspected of having the capacity to reduce the efficacy of levonorgestrel containing medication include barbiturates (including primidone), phenytoin, carbamazepine, herbal medicines containing Hypericum perforatum (St. John's Wort), rifampicin, ritonavir, rifabutin, griseofulvin, ampicillin and other antibiotics, including medicines used to treat tuberculosis, cyclosporine (see below). 
The requirement for oral antidiabetics and insulin can change as a result of an effect on glucose tolerance. 
Medicines containing levonorgestrel as in ESCAPELLE may increase the risk of cyclosporine toxicity due to possible inhibition of cyclosporine metabolism. 

PREGNANCY AND LACTATION 
Pregnancy 
ESCAPELLE should not be given to pregnant women and will not interrupt the pregnancy. In case of failure of this emergency contraception with developing pregnancy, epidemiological studies indicate no adverse effects of progestogens on the foetus. 
In case of unprotected coitus more than 72 hours earlier, the patient may be pregnant. In these cases, pregnancy should be investigated. 
Lactation 
About 0,1% of the maternal ESCAPELLE dose can be transferred via milk to the nursed infant. Potential exposure of an infant to ESCAPELLE can be reduced if the breast-feeding woman takes the tablet immediately after feeding and avoids nursing following ESCAPELLE administration. 

DOSAGE AND DIRECTIONS FOR USE 
For oral administration. The tablet should be taken no later than 72 hours after unprotected intercourse. 
ESCAPELLE can be used at any time during the menstrual cycle unless menstrual bleeding is overdue. 
After using emergency contraception it is recommended to use a local barrier method (e.g. condom) until the next menstrual period starts. The use of ESCAPELLE does not contraindicate the continuation of regular hormonal contraception. 
Children: ESCAPELLE is not recommended in children. 
Very limited data are available in women under 16 years of age. 


STORAGE INSTRUCTIONS 
Store below 25 ºC. Protect from light. 
Store in the original container until required for use. 
KEEP OUT OF REACH OF CHILDREN. 
Levonorgestrel Tablets

 

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