China Hot Sell Steroid Oil/Drug Benzyl Benzoate Take From Lab Directly, Find details about China Benzyl Benzoate, Bb from Hot Sell Steroid Oil/Drug Benzyl Benzoate Take From Lab Directly
Hot Sell Steroid Oil/Drug Benzyl benzoate Take From Lab Directly
Product details
Product Name | Benzyl benzoate |
CAS | 120-51-4 |
MF | C14H12O2 |
MW | 212.24 |
EINECS | 204-402-9 |
Melting point | 18 °C |
Boiling point | 323-324 °C(lit.) |
Density | 1.118 g/mL at 20 °C(lit.) |
vapor pressure | 1 mm Hg ( 125 °C) |
refractive index | n20/D 1.568(lit.) |
FEMA | 2138 | BENZYL BENZOATE |
Flash point | 298 °F |
storage temp | 2-8°C |
solubility | Miscible with ethanol, alcohol, chloroform, ether, oils. |
form | Liquid |
color | Clear colorless |
Water Solubility | practically insoluble |
Merck | 14,1127 |
JECFA Number | 24 |
BRN | 2049280 |
Stability | Stable. Substances to be avoided include strong oxidizing agents. Combustible. |
InChIKey | SESFRYSPDFLNCH-UHFFFAOYSA-N |
Descrotion
Benzyl benzoate (BnBzO), sold under the brand name Scabanca among others, is a medication and insect repellent. As a medication it is used to treat scabiesand lice. For scabies either permethrin or malathion is typically preferred. It is applied to the skin as a lotion. Typically two to three applications are needed.
Side effects may include irritation of the skin. It is not recommended in children. It is also used in other animals; however, is toxic to cats. How it works is unclear.
Benzyl benzoate was first studied medically in 1918. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Benzyl benzoate is available as a generic medication. The wholesale cost in the developing world is about US$0.21-0.53 per 100 mL. It is not available for medical use in the United States. In the United Kingdom it costs the NHS about £2.50 for 500 mL
Uses
Medical
Benzyl benzoate is an effective and inexpensive topical treatment for human scabies.[7] It has vasodilating and spasmolytic effects and is present in many asthmaand whooping cough drugs.[8] It is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism.[9]
Benzyl benzoate is used as a topical acaricide, scabicide, and pediculicide in veterinary hospitals.
Non-medical
Benzyl benzoate is used as a repellent for chiggers, ticks, and mosquitoes.[10] It is also used as a dye carrier, solvent for cellulose derivatives, plasticizer, and fixative in the perfume industry
Benzyl benzoate has low acute toxicity in laboratory animals. It is rapidly hydrolyzed to benzoic acid and benzyl alcohol. Benzyl alcohol is subsequently metabolized to benzoic acid. The conjugates of benzoic acid (hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine. When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia, convulsions, and respiratory paralysis.
Benzyl benzoate can be a skin irritant when used as a topical scabicide.[7] Overdose can result in blistering and hives or a rash can occur as an allergic reaction.
As an excipient in some testosterone-replacement injectable medications, benzyl benzoate has been reported as a cause of anaphylaxis in a case in Australia. Bayer includes this report in information for health professionals and recommends that physicians "should be aware of the potential for serious allergic reactions" to preparations of this type. In Australia, reports to ADRAC, which evaluates reports of adverse drug reactions for the Therapeutic Goods Administration, show several reports of allergic issues since the anaphylaxis case from 2011.
Chemistry
It is an organic compound with the formula C6H5CH2O2CC6H5. It is the ester of benzyl alcohol and benzoic acid. It forms either a viscous liquid or solid flakes and has a weak, sweet-balsamic odor. It occurs in a number of blossoms (e. g. tuberose, hyacinth) and is a component of Balsam of Peru and Tolu balsam.
Benzyl benzoate is produced industrially by the reaction of sodium benzoate with benzyl alcohol in the presence of a base, or by transesterification of methyl benzoate and benzyl alcohol. It is a byproduct of benzoic acid synthesis by toluene oxidation. It can also be synthesized by the Tishchenko reaction, using benzaldehyde with sodium benzylate (generated from sodium and benzyl alcohol) as catalyst
About our company
Wuhan Disel Biotechnoloy Co., Ltd. (shorted as Disel Biotech) is located in Wuhan Donghu High-Tech Economic Development Zone, Wuhan is a big central city in China with convenient transportation abundant human resources. Disel Biotech is a modern advanced enterprise specializing in production and exportation of APIs, peptides, plant extracts etc., has invested and closed cooperated with domestic manufacturers qualified with GMP, DMF, FDA and Laboratories from famous Universities to meet the different customers' needs from grams to tonnage quantity, which makes Disel Biotech to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers. Disel Biotech is always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers.
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Disel Biotech is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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