China Thiabendazole CAS 148-79-8, Find details about China CAS 148-79-8, Thiabendazole from Thiabendazole CAS 148-79-8
Thiabendazole Basic information | |
Product Name: | Thiabendazole |
Synonyms: | STORITE;TBZ;TBZ(R);TECTO;TECTO(R);THIBENZOLE(R);THIABENDAZOLE (TM);THIABENDAZOL |
CAS: | 148-79-8 |
MF: | C10H7N3S |
MW: | 201.25 |
EINECS: | 205-725-8 |
Thiabendazole Chemical Properties | |
Melting point | 298-301°C |
Boiling point | 446.0±37.0 °C(Predicted) |
density | 1.2271 (rough estimate) |
vapor pressure | Negligible at room temperature |
refractive index | 1.5500 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Soluble in metha nol and dimethyl sulfoxide. |
pka | pKa 4.7 (Uncertain) |
form | powder |
color | light yellow |
Water Solubility | 0.005 g/100 mL |
Description | Thiabendazole is a kind of fungicide and parasiticide. As a fungicide, it can be used for the treatment of mold, blight and many other fungal diseases occurring in fruits and vegetable. As an antiparasitic, it is capable of treating roundworms, hookworms, and other kinds of helminth species that can attack wild animals, livestock and humans. It also has effects of inhibiting the angiogenesis of cells. The mechanism of action is still not fully understood. It has found that Thiabendazole is capable of suppressing the helminth-specific mitochondrial enzyme fumarate reductase, further inhibiting the citric acid cycle, mitochondrial respiration and ATP production, leading to helminth's death. It may also inhibit the microtubule polymerization processes. |
Uses | A drug used in the treatment of helminthiases |
anticoagulant, rodenticide | |
Thiabendazole is widely used as a post-harvest systemic fungicide on citrus and bananas. It is active against fruit rots in bananas, citrus, apples and pears; bulb and corm rots in ornamentals; storage rots in sweet potato and potato and is also used to control Dutch elm disease. It is the original benzimidazole anthelmintic for both human and animal health usages. |
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