GS-441524 is a small molecule with a scientific name of nucleoside triphosphate competitive inhibitor, which shows strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute Chemicalbook respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory tract Syncytial virus, etc., have low cytotoxicity in a wide range of cell lines.