Ampicillin Sodium and Sulbactam Sodium API
This product is white or nearly white powder or crystalline powder.
Pharmacology and Toxicology
Ampicillin sodium is a kind of penicillin antibiotics. Sulbactam sodium is a semi synthetic (lactamase inhibitor, which has strong antibacterial activity against Neisseria gonorrhoeae, Neisseria meningitidis and Acinetobacter calcium acetate, but it has very poor effect on other bacteria, but it has strong irreversible competitive inhibitory effect on Staphylococcus aureus and most Gram-negative bacteria. The combination of the two drugs not only protects ampicillin from enzymatic hydrolysis, but also expands its antibacterial spectrum. It also has good antibacterial activity against Staphylococcus, Acinetobacter and Bacteroides fragilis. The product has antibacterial activity against Staphylococcus, Streptococcus, pneumococcus, Enterococcus, Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, Klebsiella, Proteus mirabilis, Proteus vulgaris, Neisseria gonorrhoeae, Fusobacterium, Enterococcus, Streptococcus digest and Bacteroides including Bacillus fragilis.