API CAS 53123-88-9 Sirolimus Material Sirolimus Powder Raw Powder Rapamycin Sirolimus
China API CAS 53123-88-9 Sirolimus Material Sirolimus Powder Raw Powder Rapamycin Sirolimus, Find details about China Sirolimus, Rapamycin Sirolimus from API CAS 53123-88-9 Sirolimus Material Sirolimus Powder Raw Powder Rapamycin Sirolimus
Basic Info.
Model NO.
D-sung Sirolimus
Product Name
Sirolimus
Name
Rapamycin
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Antineoplastic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
53123-88-9
Mf
C51h79no13
MW
914.17186
Boiling Point
973.017 Oc at 760 Mmhg
Density
1.182
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Sirolimus
Product Name
Sirolimus
Name
Rapamycin
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Antineoplastic
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
53123-88-9
Mf
C51h79no13
MW
914.17186
Boiling Point
973.017 Oc at 760 Mmhg
Density
1.182
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
API CAS 53123-88-9 Sirolimus Material Sirolimus Powder Raw Powder Rapamycin Sirolimus
| Product name | Sirolimus |
| Cas number | 53123-88-9 |
| Appearance | White powder |
| MF | C51H79NO13 |
| MW | 914.17186 |
Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2).
Sirolimus is indicated for the prevention of organ transplant rejection and for the treatment oflymphangioleiomyomatosis
Rapamycin initially was taken as low toxicity antifungal drugs, and was found immunosuppressive in 1977. From 1989, RAPA was as a new drug for the treatment of organ transplantation rejection in trial, and from animal experiments and clinical application effects, it is of good curative effects, low toxicity and no new immunosuppressant nephrotoxicity.
Now rapamycin is frequently as maintaining immunity drug for transplant organs (especially kidney transplant), to slow down the immune rejection of the organ in transplant surgery, however, scientists recently discovered another purpose: it can be used in the treatment of alzheimer's disease (senile dementia).
Medical researchers from University of Chicago combined commercially available rapamycin oral tablets with grapefruit juice in the treatment of melanoma (a kind of malignant tumor disease common in European and American people), which could greatly improve the anticancer effect of other chemotherapy drugs, thereby prolong the survival time of patients.
Rapamycin initially was taken as low toxicity antifungal drugs, and was found immunosuppressive in 1977. From 1989, RAPA was as a new drug for the treatment of organ transplantation rejection in trial, and from animal experiments and clinical application effects, it is of good curative effects, low toxicity and no new immunosuppressant nephrotoxicity.
Now rapamycin is frequently as maintaining immunity drug for transplant organs (especially kidney transplant), to slow down the immune rejection of the organ in transplant surgery, however, scientists recently discovered another purpose: it can be used in the treatment of alzheimer's disease (senile dementia).
Medical researchers from University of Chicago combined commercially available rapamycin oral tablets with grapefruit juice in the treatment of melanoma (a kind of malignant tumor disease common in European and American people), which could greatly improve the anticancer effect of other chemotherapy drugs, thereby prolong the survival time of patients.
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