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Manufacturer Supply 99% Original Powder Rapamycin CAS 53123-88-9 with Safe Delivery

China Manufacturer Supply 99% Original Powder Rapamycin CAS 53123-88-9 with Safe Delivery, Find details about China Rapamycin Powder, Rapamycin Sirolimus from Manufacturer Supply 99% Original Powder Rapamycin CAS 53123-88-9 with Safe Delivery

Trademark
BYYQ
Specification
99.9%
Origin
China
HS Code
2917120001
Trademark
BYYQ
Specification
99.9%
Origin
China
HS Code
2917120001

Product Description

Rapamycine is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production.

Rapamycine is a potent immunosuppressant, and have both antifungal and antineoplastic properties.
 
Product NameRapamycin
CAS No.53123-88-9
Appearance

White or almost white powder

Assay97.5%~102.0%(on dried basis)

Function
It is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It inhibits activation of T cells and B cells by reducing the production of interleukin-2 (IL-2).

Rapamycin is a triene macrolide antibiotic,which demonstrates anti-fungal,anti-inflammatory,anti-tumor and immunosuppressive properties.
Rapamycin has been shown to block T-cell activation and proliferation,as well as,the activation of p70 S6 kinase and exhibits strong binding to FK506 binding proteins.
Rapamycin also inhibits the activity of the protein,mTOR(mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth.
Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

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