Thiamphenicol Capsules for Respiratory Tract, Urinary Tract, Intestinal Tract Infection Caused by Sensitive Bacteria
China Thiamphenicol Capsules for Respiratory Tract, Urinary Tract, Intestinal Tract Infection Caused by Sensitive Bacteria, Find details about China Thiamphenicol Capsules, Thiamphenicol from Thiamphenicol Capsules for Respiratory Tract, Urinary Tract, Intestinal Tract Infection Caused by Sensitive Bacteria
Basic Info.
Model NO.
CF063
Model NO.
CF063
Product Desciption
[Drug name]
General name: sulfoxamycin capsule
Product name: sulfoxamycin capsule
English name: Thiamphenicol Capsules
Pinyin full code: Jiafengmeisujiaonang (Renfu)
Main ingredients The main ingredients of this product are: sulfoxamycin. Its chemical name is: [R - N - (R * R *) {1 - (hydroxy methyl) - 2 - hydroxy - 2 - [4 - (methyl sulfonyl) phenyl ethyl} (2, 2 - dichloro acetyl.
"Into a"
Molecular Weight: C12H15Cl2NO5s
This product is a capsule.
[Indications/Functional Indications] Used for respiratory tract, urinary tract, intestinal tract infection caused by sensitive bacteria such as Haemophilus influenzae, Escherichia coli, Salmonella, etc.
[Specification model] 0.25g*10s
[Usage and Dosage] Oral administration, adult 1.5 ~ 3g a day, divided into 3 ~ 4 times, children according to body weight 25 ~ 50mg/Kg a day, divided into 4 times.
[Adverse Reactions] 1. Abdominal pain, diarrhea, nausea, vomiting and other digestive tract reactions can occur, the incidence of which is less than 10%. 2. Occasional rash and other allergic reactions. 3. No "grey baby syndrome" has been found in premature infants and newborns. Transient skin and pallor have only been reported in isolated cases. 4. This product can also cause toxic reactions in the hematopoietic system, mainly manifested as reversible inhibition of erythropoiesis, leukopenia and thrombocytopenia; Aplastic anemia is rare. 5. The main manifestations of central nervous system reactions were headache, drowsiness, dizziness and peripheral neuritis. The person that has nervous system pathological change accepts sulfone mycin for a long time to treat, can cause the symptom such as tactile decrease, touch feeling pain and hyperalgesia. The symptoms of the feet were more serious than those of the hands, which improved after discontinuation of the drug, but could not be completely recovered.
[prohibited] It is prohibited for people who are allergic to this product.
[Precautions] 1. During the treatment, patients should check the peripheral blood image regularly. If the treatment course is longer, the reticulocyte count should be checked, and adverse reactions of the blood system should be found at the same time. 2. The sulfoxamycin excretion is reduced in patients with renal insufficiency, and there may be a tendency to accumulate in the body, so the dosage should be reduced. 3. The medication of elderly patients should be adjusted according to renal function. Please read the instructions carefully and follow the doctor's advice.
[Children's medicine] Avoid use in newborns.
[Drug use in elderly patients] is not clear.
[Pregnant women and lactating women medication] pregnancy, especially late pregnancy women should try to avoid the use of drugs, lactating women should be suspended breastfeeding.
[Drug interaction] 1. Antiepileptic drugs (acetonylurea). Because this product can inhibit the activity of liver cell microsomal enzyme, resulting in a decrease in the metabolism of this drug, or this product to replace the serum protein binding site of this drug, can enhance the action of the drug or increase the toxicity, so it is necessary to adjust the dosage of this drug when combined with this product or in the subsequent application. 2. When combined with hypoglycemic drugs (such as toluene sulfonamide), the hypoglycemic effect can be enhanced due to the replacement of the protein binding site, so the dosage of such drugs should be adjusted. The non-ionic binding characteristics of glipizide and glibenclamide were less affected than those of other oral hypoglycemic agents, but caution should be taken when they are combined. 3. When long-term oral contraceptives containing estrogen are taking this product at the same time, the reliability of contraception can be reduced, and the blood will increase during menstruation. 4. As this product may act as a vitamin B6 antagonist or increase transrenal excretion of the latter, anemia or peripheral neuritis may result. Therefore, when this product is used together with vitamin B6, the dose of the latter should be increased appropriately. 5. This product can antagonize the hematopoietic action of vitamin BL2, so they should not be used together. 6. When used in combination with some myelosuppressive drugs, it can enhance myelosuppressive effects. Anticancer drugs, colchicine, hydroxyl butazone, butazone and penicillamine are among these drugs. The myelosuppressive effect can also be enhanced when radiotherapy is given at the same time. The dose of bone marrow inhibitor or radiotherapy should be adjusted. 7. If applied preoperatively or intraoperatively, this product can reduce the clearance of induced anaesthetic alfentanil and prolong its action time due to its inhibitory effect on liver enzymes. 8. Phenobarbital and rifamequin liver drug enzyme inducers, when used together with this product, can enhance the metabolism of this product and reduce the blood concentration of sulfoxamycin. 9. Lincomycin can replace or prevent the combination of Lincomycin with the 50S subunit of bacterial ribosomes. The combination of Lincomycin and Lincomycin can antagonize the 50S subunit of bacterial ribosomes, so it is not suitable to be used together.
[Drug overdose] is not clear.
[Pharmacological Toxicology] This product is a similar to chloramphenicol, antibacterial spectrum and antibacterial action similar to chloramphenicol, with a broad spectrum of antimicrobial action, including aerobic Gram-negative bacteria and Gram-positive bacteria, anaerobic bacteria, Rickettsia, spirochetes and chlamydia. Sulfoxamycin has bactericidal activity against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis. It has only bacteriostatic effect on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus virifolia, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus singularis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are generally resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marxygii, Indole positive Proteus, Methicillin-resistant Staphylococcus, and Enterococcus. This product is a bacteriostasis agent, which reversibly binds to the 50S subunit of the bacterial ribosome, impeding the growth of the peptide chain (possibly due to the inhibition of transpeptidase action), thus inhibiting the formation of the peptide chain, thus preventing the synthesis of protein, and showing complete cross-resistance to chloramphenicol. Since sulfoxamycin does not bind to glucuronic acid in the liver, it has high antibacterial activity in vivo. This product still has strong immunosuppressive effect, about 6 times stronger than chloramphenicol.
Pharmacokinetics This product is absorbed rapidly and completely after oral administration, and the plasma concentration of normal people reaches the peak of 4mg/L 2 hours after oral administration of 400mg. As the dose increased, the blood concentration increased correspondingly. Continuous drug use has no accumulation in the body. After absorption, sulfoxamycin is widely distributed in the body, with higher content in kidney, spleen, liver, lung and so on, about 3 ~ 4 times higher than the same dose of chloramphenicol. Blood elimination half-life (t1/2?) About 1.5 hours, people with normal renal function can discharge 70% ~ 90% of the drug dose from urine within 24 hours, and part of the drug is excreted from bile, which can be dozens of times of the blood drug concentration. Sulfoxamycin is not metabolized in the body, so blood drug concentration is not affected when liver function is abnormal.
[Storage] Shading sealed, put in a dry place.
[Effective period] 24 months
[Executive standard] "Chinese Pharmacopoeia", 2005 edition 2
[Approval Number] National medicine approval H42022055
FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.
4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.
5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese
Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages
Our Service
a) Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.
Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
Factory View
Our Products
Our Business
General name: sulfoxamycin capsule
Product name: sulfoxamycin capsule
English name: Thiamphenicol Capsules
Pinyin full code: Jiafengmeisujiaonang (Renfu)
Main ingredients The main ingredients of this product are: sulfoxamycin. Its chemical name is: [R - N - (R * R *) {1 - (hydroxy methyl) - 2 - hydroxy - 2 - [4 - (methyl sulfonyl) phenyl ethyl} (2, 2 - dichloro acetyl.
"Into a"
Molecular Weight: C12H15Cl2NO5s
This product is a capsule.
[Indications/Functional Indications] Used for respiratory tract, urinary tract, intestinal tract infection caused by sensitive bacteria such as Haemophilus influenzae, Escherichia coli, Salmonella, etc.
[Specification model] 0.25g*10s
[Usage and Dosage] Oral administration, adult 1.5 ~ 3g a day, divided into 3 ~ 4 times, children according to body weight 25 ~ 50mg/Kg a day, divided into 4 times.
[Adverse Reactions] 1. Abdominal pain, diarrhea, nausea, vomiting and other digestive tract reactions can occur, the incidence of which is less than 10%. 2. Occasional rash and other allergic reactions. 3. No "grey baby syndrome" has been found in premature infants and newborns. Transient skin and pallor have only been reported in isolated cases. 4. This product can also cause toxic reactions in the hematopoietic system, mainly manifested as reversible inhibition of erythropoiesis, leukopenia and thrombocytopenia; Aplastic anemia is rare. 5. The main manifestations of central nervous system reactions were headache, drowsiness, dizziness and peripheral neuritis. The person that has nervous system pathological change accepts sulfone mycin for a long time to treat, can cause the symptom such as tactile decrease, touch feeling pain and hyperalgesia. The symptoms of the feet were more serious than those of the hands, which improved after discontinuation of the drug, but could not be completely recovered.
[prohibited] It is prohibited for people who are allergic to this product.
[Precautions] 1. During the treatment, patients should check the peripheral blood image regularly. If the treatment course is longer, the reticulocyte count should be checked, and adverse reactions of the blood system should be found at the same time. 2. The sulfoxamycin excretion is reduced in patients with renal insufficiency, and there may be a tendency to accumulate in the body, so the dosage should be reduced. 3. The medication of elderly patients should be adjusted according to renal function. Please read the instructions carefully and follow the doctor's advice.
[Children's medicine] Avoid use in newborns.
[Drug use in elderly patients] is not clear.
[Pregnant women and lactating women medication] pregnancy, especially late pregnancy women should try to avoid the use of drugs, lactating women should be suspended breastfeeding.
[Drug interaction] 1. Antiepileptic drugs (acetonylurea). Because this product can inhibit the activity of liver cell microsomal enzyme, resulting in a decrease in the metabolism of this drug, or this product to replace the serum protein binding site of this drug, can enhance the action of the drug or increase the toxicity, so it is necessary to adjust the dosage of this drug when combined with this product or in the subsequent application. 2. When combined with hypoglycemic drugs (such as toluene sulfonamide), the hypoglycemic effect can be enhanced due to the replacement of the protein binding site, so the dosage of such drugs should be adjusted. The non-ionic binding characteristics of glipizide and glibenclamide were less affected than those of other oral hypoglycemic agents, but caution should be taken when they are combined. 3. When long-term oral contraceptives containing estrogen are taking this product at the same time, the reliability of contraception can be reduced, and the blood will increase during menstruation. 4. As this product may act as a vitamin B6 antagonist or increase transrenal excretion of the latter, anemia or peripheral neuritis may result. Therefore, when this product is used together with vitamin B6, the dose of the latter should be increased appropriately. 5. This product can antagonize the hematopoietic action of vitamin BL2, so they should not be used together. 6. When used in combination with some myelosuppressive drugs, it can enhance myelosuppressive effects. Anticancer drugs, colchicine, hydroxyl butazone, butazone and penicillamine are among these drugs. The myelosuppressive effect can also be enhanced when radiotherapy is given at the same time. The dose of bone marrow inhibitor or radiotherapy should be adjusted. 7. If applied preoperatively or intraoperatively, this product can reduce the clearance of induced anaesthetic alfentanil and prolong its action time due to its inhibitory effect on liver enzymes. 8. Phenobarbital and rifamequin liver drug enzyme inducers, when used together with this product, can enhance the metabolism of this product and reduce the blood concentration of sulfoxamycin. 9. Lincomycin can replace or prevent the combination of Lincomycin with the 50S subunit of bacterial ribosomes. The combination of Lincomycin and Lincomycin can antagonize the 50S subunit of bacterial ribosomes, so it is not suitable to be used together.
[Drug overdose] is not clear.
[Pharmacological Toxicology] This product is a similar to chloramphenicol, antibacterial spectrum and antibacterial action similar to chloramphenicol, with a broad spectrum of antimicrobial action, including aerobic Gram-negative bacteria and Gram-positive bacteria, anaerobic bacteria, Rickettsia, spirochetes and chlamydia. Sulfoxamycin has bactericidal activity against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis. It has only bacteriostatic effect on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus virifolia, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus singularis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are generally resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marxygii, Indole positive Proteus, Methicillin-resistant Staphylococcus, and Enterococcus. This product is a bacteriostasis agent, which reversibly binds to the 50S subunit of the bacterial ribosome, impeding the growth of the peptide chain (possibly due to the inhibition of transpeptidase action), thus inhibiting the formation of the peptide chain, thus preventing the synthesis of protein, and showing complete cross-resistance to chloramphenicol. Since sulfoxamycin does not bind to glucuronic acid in the liver, it has high antibacterial activity in vivo. This product still has strong immunosuppressive effect, about 6 times stronger than chloramphenicol.
Pharmacokinetics This product is absorbed rapidly and completely after oral administration, and the plasma concentration of normal people reaches the peak of 4mg/L 2 hours after oral administration of 400mg. As the dose increased, the blood concentration increased correspondingly. Continuous drug use has no accumulation in the body. After absorption, sulfoxamycin is widely distributed in the body, with higher content in kidney, spleen, liver, lung and so on, about 3 ~ 4 times higher than the same dose of chloramphenicol. Blood elimination half-life (t1/2?) About 1.5 hours, people with normal renal function can discharge 70% ~ 90% of the drug dose from urine within 24 hours, and part of the drug is excreted from bile, which can be dozens of times of the blood drug concentration. Sulfoxamycin is not metabolized in the body, so blood drug concentration is not affected when liver function is abnormal.
[Storage] Shading sealed, put in a dry place.
[Effective period] 24 months
[Executive standard] "Chinese Pharmacopoeia", 2005 edition 2
[Approval Number] National medicine approval H42022055
FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.
4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.
5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese
Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages
Our Service
a) Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.
Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
Factory View
Our Products
Our Business
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