Gastrointestinal problems
There is some evidence that domperidone has antiemetic activity. Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.
It can be used in patients with Parkinson's disease because, unlike metoclopramide, domperidone does not cross the blood-brain barrier.
Domperidone has also been found effective in the treatment of gastroparesis, a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).
In Canada, the drug is indicated "for the symptomatic management of upper gastrointestinal motility disorders associated with chronic and subacute gastritis and diabetic gastroparesis." The drug may also be used "to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents".

Application

Domperidone is a peripherally selective dopamine D2receptor antagonist developed by Janssen Pharmaceutica that is used as an antiemetic, gastroprokinetic agent, and galactogogue.It may be administered orally or rectally, and is available in the form of tablets,orally disintegrating tablets (based on Zydis technology), suspension, and suppositories.The drug is used to relieve nausea and vomiting; to increase the transit of food through the stomach (by increasinggastrointestinal peristalsis); and to promote lactation (breast milk production) by release of prolactin.

Specification
 

Package & Delivery