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CB-03-01 Hair Loss Treatment Raw Powder CAS 19608 -29-8 CB-03-01

China CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01, Find details about China CB-03-01, CAS 19608-29-8 from CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01

Model NO.
KL-CB
Trademark
JULONG
Transport Package
1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require
Specification
99%
Origin
China
HS Code
29309090
Model NO.
KL-CB
Trademark
JULONG
Transport Package
1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require
Specification
99%
Origin
China
HS Code
29309090

  CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01
CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01Product Information:        
Product NameCB-03-01
CAS No19608-29-8  
M.F.C24H34O5
GradePharmaceutical Grade
ColorWhite powder
Purity99%
Shelf Life2 years
Description:
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate,
is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a
topical medication in the treatment of androgen - dependent conditions including acne vulgaris and rog-
enic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone)
; C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexo
-lone 17α-propionate was selected for development based on its optimum drug profile.
CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01
Function:
CB-03-01 is the drug for the treatment of hair loss dwindled. It has same function and application with
RU58841 and Setipiprant. CB-03-01 is a molecule that acts at the level of the skin, blocking dihydrot-
estosterone (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that
acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally
found in the body. The molecule has been evaluated in a variety of animal models as well as initial hu-
man trials in Europe. The results of these studies demonstrate that CB-03-01 appears to have potent ac-
tivity without significant local or systemic side effects.
Application:   
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate,
is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a to-
pical medication in the treatment of androgen-dependent conditions including acne vulgaris and androge-
nic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C-
17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone
- 17α-propionate was selected for development based on its optimum drug profile.              CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01COA:

Items

Requirements

Results

Appearance:

White Powder

 White Powder

Identification

HPLC

IR spectra is consistent with CRS

Conforms

Sulphated Ash 

≤0.1%

0.01%

Loss on drying

≤0.5%

0.38%

Related substances 

Impurity A ≤0.1%

Impurity B ≤0.2%

Any other Impurity ≤0.1%

All other Impurity A ≤0.2%

<0.1%

<0.2%

<0.1%

<0.2%

Heavy metal

Pb :

Cadmium(Cd) :

As :

Hg:

≤ 10ppm

<1 ppm

<0.5 ppm

<10ppm

< 1 ppm

<10ppm

Conforms

0.3ppm

Conforms

Negative

Assay

≥99%99.5%

Conclusion:

The product conforms to BP.


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CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01CB-03-01 Hair Loss Treatment Raw Powder CAS 19608-29-8 CB-03-01

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