China High Purity Dyclonine Hydrochloride CAS 536-43-6 Dyclonine HCl Powder, Find details about China Dyclonine Hydrochloride, CAS 536-43-6 from High Purity Dyclonine Hydrochloride CAS 536-43-6 Dyclonine HCl Powder
Product Name: Dyclonine hydrochloride
Synonyms: DYCLONINE HCL;DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride;dyclonine hydrochlorideinoline-3-carboxylic acid;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone chloride
CAS: 536-43-6
MF: C18H28ClNO2
MW: 325.87
EINECS: 208-633-6
Melting point: 175-176°C
Boiling point: 329.1±15.0 °C
Density: 1.137±0.06 g/cm3
Storage temp.: -20°C Freezer
Appearance: White Powder
Description:
Dyclonine hydrochloride is the hydrochloride salt of Dyclonine. Dyclonine belongs to a kind of oral anaesthetic. It is contained in the "Sucrets" as well as some kinds of Cepacol sore throat spray as an active ingredient. Dyclonine takes effect through reversibly binding to the activated sodium channels located on the neuronal membrane. This decreases the permeability of sodium across the neuronal membrane, further increasing the threshold for excitation. Overall, Dyclonine stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and further suppressing the subsequent conduction. This causes a transient and reversible anaesthetic effect in a local area of the body.
Uses:
Dyclonine hydrochloride is used for the temporary relief of the following occasional mouth and throat symptoms: pain, minor irritation, sore mouth and sore throat. It is a sodium channel blocker and a HSP90 chaperone protein inhibitor. It shows local anesthetic effects in vivo and is orally active.
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