China Top Quality Amifostine CAS 20537-88-6, Find details about China Amifostine, CAS 20537-88-6 from Top Quality Amifostine CAS 20537-88-6
Product Name: Amifostine
Synonyms: Ethyol;γphos;Fosteamine;2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;Ethiotas;S-2-[(3-Aminopropyl)amino]etha nethiol dihydrogen phosphate ester;Amifostine,2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;AMifostine anhydrous
CAS: 20537-88-6
MF: C5H15N2O3PS
MW: 214.22
EINECS: 633-786-4
Melting point: 160-161°C
Boiling point: 441.7±51.0 °C
Storage temp.: 2-8°C
Description:
Amifostine, an organic thiophosphate, was introduced for the reduction of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated, preferentially in non-tumor tissues to the active thiol. This agent binds to chemotherapeutic drugs and free radicals released by radiotherapy. The protective effect of amifostine was observed in a wide range of normal organs including bone marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of chemohadiotherapy, indicating an increased therapeutic index for existing cancer treatment. Amifostine is also being evaluated as a cytoprotective in other types of tumors including lung, breast, head and neck cancers. It was reported to be a potent mucolytic with potential in cystic fibrosis.
Usage:
It is a thiophosphate derivative of cysteamine; provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment
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Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.
Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei