China Hot Sale Hair Loss Treatment CB-03-01 19608-29-8, Find details about China CB-03-01, Oral Care Chemicals from Hot Sale Hair Loss Treatment CB-03-01 19608-29-8
Basic Information:
Product Name: CB-03-01
Appearance:White powder
Purity: 98%min by HPLC
CAS No.: 19608-29-8
Appearance: White powder
M.W.: 402.531
M.F.: C24H34O5
Assay: HPLC; HNRM; LC-MS
Product Description:
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
Function:
CB-03-01 is the drug for the treatment of hair loss dwindled. It has same function and application with RU58841 and Setipiprant.
CB-03-01 is a molecule that acts at the level of the skin, blocking dihydrotestosterone (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe. The results of these studies demonstrate that CB-03-01 appears to have potent activity without significant local or systemic side effects.
FAQ
Application Area:
Uridine 5-Mophosphate Disodium are produced through the hydrolytic reaction from Ribonucleic acid(RNA) as raw material by enzymatic catalysis to form four kinds of nucleotides 5- 'AMP (adenosine-5'-monophosphate), 5'-GMP•2Na(guanosine-5'-monophosphate, disodium salt), 5'-CMP(cytidine-5'-monophosphate)-, 5'-UMP•2Na (uridine- 5'-monophosphate,Disodium salt) .By the chromatographic isolation, four kinds of separated 5'-nucleotide products with high purity can be obtained. These products can be widely applied in medicine, reagent, fine chemical industry, and additive of food fields etc.