Pharmaceutical CAS 503612 -47-3 Apixaban Purity Apixaban Powder Raw Powder Apixaban
China Pharmaceutical CAS 503612-47-3 Apixaban Purity Apixaban Powder Raw Powder Apixaban, Find details about China Apixaban, Intermediate Apixaban from Pharmaceutical CAS 503612-47-3 Apixaban Purity Apixaban Powder Raw Powder Apixaban
Basic Info.
Model NO.
D-sung Apixaban
Product Name
Apixaban
Name
Apixaban Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Anticoagulants
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
503612-47-3
Mf
C25h25n5o4
MW
459.506
Density
1.42
Boiling Point
770.468°c at 760 Mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Apixaban
Product Name
Apixaban
Name
Apixaban Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical;Anticoagulants
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
503612-47-3
Mf
C25h25n5o4
MW
459.506
Density
1.42
Boiling Point
770.468°c at 760 Mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Pharmaceutical CAS 503612-47-3 Apixaban Purity Apixaban Powder Raw Powder Apixaban
| Product name | Apixaban |
| Appearance | White powder |
| Cas number | 503612-47-3 |
| MF | C25H25N5O4 |
| MW | 459.506 |
Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.
Function of apixaban
1. Apixaban is used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation)
2. Apixaban used for treating and preventing deep venous thrombosis (DVT) and pulmonary embolism in patients who have undergone hip or knee replacement surgery.
Application of apixaban
1) Apixaban is factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke.
2) Apixaban also have effect i systemic in patients with nonvavular atrial fibrillation.
Function of apixaban1. Apixaban is used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation)
2. Apixaban used for treating and preventing deep venous thrombosis (DVT) and pulmonary embolism in patients who have undergone hip or knee replacement surgery.
Application of apixaban
1) Apixaban is factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke.
2) Apixaban also have effect i systemic in patients with nonvavular atrial fibrillation.
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