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Rimonabant Lose Weight Pharmaceutical Raw Powder CAS 168273-06-1

China Rimonabant Lose Weight Pharmaceutical Raw Powder CAS 168273-06-1, Find details about China Rimonabant, Pharmaceutical Raw Powder from Rimonabant Lose Weight Pharmaceutical Raw Powder CAS 168273-06-1

Transport Package
Foil Bag
Specification
Powder
Origin
China
Transport Package
Foil Bag
Specification
Powder
Origin
China
Rimonabant Lose Weight Pharmaceutical Raw Powder CAS 168273-06-1
 

Description

Product name : Rimonabant
Other name : ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716)
CAS : 168273-06-1
MF : C22H21Cl3N4O
MW: 463.79
Assay : 99%
Appearance:White Powder
Usage : Weight loss powders/ Rimonabant is a selective antagonist

Rimonabant is said to have reduced the overall body fat by 10% in one out of three users. Also, it is reported that those users did not gain back more than a kilo over the next two years if the patients remained on Rimonabant. Rimonabant was recommended for those with a BMI of 30 or greater, who were considered obese, and is most successful when combined with exercise and a proper diet. It was not recommended for those who just wanted to lose a few pounds. Rimonabant is valuable in smoking cessation therapy, and initial results are positive.


Specification

Test ItemsSpecificationTest Results
DescriptionWhite crystalline powderWhite crystalline powder
IdentificationIR , UV conformConform
Loss on drying≤0.5ml0.21ml
Residue on ignitionNot more than 0.2%0.06ml
IronNot more than 0.005%0.0018%
Heavy metalsNot more than 0.001%0.0006%
Related substancesTotal: Not more than 1.0%
Individual: Not more than 0.5%		0.32%
0.14%
E-isomerNot more than 0.3%0.19%
Organic volatile impuritiesConformsConforms
Assay99.0~101.0%99.51%
ConclusionConform with USP30
Rimonabant Lose Weight Pharmaceutical Raw Powder CAS 168273-06-1

What is Rimonabant ?

 

Acomplia (rimonabant) was the first in a new class of therapeutic agents called Cannabinoid-1 Receptor Blockers (CB1).


Rimonabant was studied for use in the treatment of obesity and related conditions.

 

How does Rimonabant work?

 

Rimonabant acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle2.


Rimonabant switches off the same brain circuits that make people hungry when they smoke cannabis.
CB1 receptor blockade with Rimonabant acts to decrease the overactivity of the endocannabinoid system (EC system).3,4 The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

 

What is Rimonabant used for?

 

Rimonabant was studied to be used complementary to diet and exercise to treat obese or overweight patients who suffer from type 2 diabetes and abnormal levels of fat in the blood.
Sanofi argued that Rimonabant could also prevent the risk of cardiovascular disease.
Patients with large waist circumference (102 cm in men and 88 cm in women) were said to most benefit from taking the drug.

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