Thiamphenicol Powder 10% Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use

China Thiamphenicol Powder 10% Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use, Find details about China Thiamphenicol, Antibiotic from Thiamphenicol Powder 10% Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use

Basic Info.

Model NO.

Premix Powder

Trademark

JIUDING

Transport Package

Carton

Specification

5%, 50g/100g/150g/200g/250g/500g

Origin

China

HS Code

3004909099

Model NO.

Premix Powder

Trademark

JIUDING

Transport Package

Carton

Specification

5%, 50g/100g/150g/200g/250g/500g

Origin

China

HS Code

3004909099

Product Desciption

Thiamphenicol Powder 5%
FOR VETERINARY USE

Composition:
Per 1 gram contains
Thiamphenicol 50mg

Description:
This product is white powder.

Pharmacological Action:
Pharmacodynamics
Thiamphenicol is an amide alcohol antibacterial drug with a broad-spectrum antibacterial effect. It has a stronger effect on Gram-negative bacteria than Gram-positive bacteria. It has a stronger effect on most Enterobacteriaceae, including typhoid bacillus, paratyphoid bacillus, and Escherichia coli. Helicobacter and Salmonella are highly sensitive, and the susceptible Gram-negative bacteria include Pasteurella and Brucella. Sensitive Gram-positive bacteria include Bacillus anthracis, Streptococcus, Corynebacterium, Pneumococcus, Staphylococcus and so on. Chlamydia, Leptospira and Rickettsia are also sensitive to this product. It also has a considerable effect on anaerobic bacteria such as Clostridium tetani and actinomycetes. But Mycobacterium tuberculosis, Pseudomonas aeruginosa, and fungi are not sensitive to it.
Pharmacokinetics
This product is absorbed quickly and completely when taken orally. After being absorbed, it is widely distributed in various tissues in the body. It is mainly excreted in the urine in its original form. The half-life of cattle and sheep is shorter than that of chloramphenicol, and the half-life of pigs is 4.2 hours.

Drug Interactions:
(1) Macrolides and lincosamides have the same target of action as this product, both of which are similar to the bacterial nucleus.
Glycosome 50S subunits are combined and can produce antagonistic effects when used in combination.
(2) When combined with β-lactams, this product can produce antagonistic effects due to its rapid antibacterial effect.
(3) It has an inhibitory effect on liver microsomal drug-metabolizing enzymes, which can affect the metabolism of other drugs, increase blood drug concentration, and enhance drug efficacy or toxicity. For example, it can significantly extend the anesthesia time of pentobarbital sodium.

Indications:
Amido alcohol antibiotics. It is mainly used to treat bacterial infections such as the intestines and respiratory tracts of livestock and poultry and bacterial diseases of fish.

Dosage and Administration:
For oral administration:
Livestock and Poultry: 1-2 g for per 10 kg of body weight. Use it twice a day for 2 to 3 times.
Fish: Mixed bait feeding, 50g per 150kg body weight, once a day for 3 to 4 days.

Adverse Reactions:
(1) This product is toxic to the blood system. Although it will not cause aplastic anemia, the reversible erythropoiesis inhibition caused by it is more common than chloramphenicol.
(2) This product has a strong immunosuppressive effect, about 6 times stronger than chloramphenicol.
(3) Long-term oral administration can cause digestive disorders, symptoms of vitamin deficiency or double infection.
(4) Embryonic toxicity.
(5) It has an inhibitory effect on liver microsomal drug-metabolizing enzymes, which can affect the metabolism of other drugs, increase blood drug concentration, and enhance drug efficacy or toxicity. For example, it can significantly extend the anesthesia time of pentobarbital sodium.

Precautions:
(1) Animals with severely impaired immune function during the vaccination period are prohibited.
(2) Use with caution for livestock during pregnancy and lactation.
(3) Animals with renal insufficiency should reduce the dose or extend the interval between administrations.

Withdrawal Period:
For meat: 28 days;
For milk: 7 days;
For fish: 500 degree days.

Package:
50g, 100g, 150g, 200g, 250g, 500g

Storage:
Sealed and Stored in a cool and dry place.

Shelf Life:
3 years.

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