China Faithful Supply Imperatorin 482-44-0//Chlorzoxazone 95-25-0//Tenofovir 147127-20-6//Entecavir 142217-69-4//Memantine Hydrochloride 41100-52-1 Memantine HCl, Find details about China Memantine HCl, Memantine Hydrochloride from Faithful Supply Imperatorin 482-44-0//Chlorzoxazone 95-25-0//Tenofovir 147127-20-6//Entecavir 142217-69-4//Memantine Hydrochloride 41100-52-1 Memantine HCl
Introduction
Product Name | Memantine Hydrochloride/Memantine HCL |
CAS No. | 41100-52-1 |
Molecular Formula | C12H22ClN |
Molecular Weight | 215.76 |
Appearance | White Powder |
Assay | 99% |
Grade | Pharmaceutical Grade |
Brand | Faithful |
Function
Memantine Hydrochloride is a raw material medicine and is made into a tablet called "Easy". This product should be prescribed and guided by experienced doctors for the diagnosis and treatment of Alzheimer's type dementia. Treatment can only begin if the patient is surrounded by a caregiver who supervises the patient's medication on time. Dementia should be diagnosed in accordance with current diagnostic criteria and guidelines.
Is a novel, low-to-moderate, voltage-dependent, non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that non-competitively blocks NMDA receptors and reduces glutamate Excessive excitability of NMDA receptors, prevention of apoptosis, and improvement of memory are new generations of drugs that improve cognitive function. As a chemical, memantine hydrochloride lacks some basic physical properties. It can be considered that some of the properties of adamantane, amantadine hydrochloride, and 1,3-dimethyladamantane are presumed to be soluble in organic solvents and slightly soluble in water. Low toxicity, no irritating effect on skin, eyes and mucous membranes, but as a medicine, it must be used under the guidance of the doctor, and must not be swallowed at will.
Application
Specification
Item | Requirements | Test Results |
appearance | White or almost white crystalline powder | White Crystalline Powder |
Identification | IR | Conforms |
Related substance | 1-methyladamantane ≤0.3% 1,3,5 -trimethyladamantane ≤0.3% Unknow impuritiy ≤0.1% Total impurity ≤0.5% | 0.13% 0.14% <0.1% <0.4% |
Residue on ignition | ≤0.1% | 0.06% |
Heavy matal | ≤10ppm | <10ppm |
Loss on drying | ≤0.5% | 0.29% |
Assay | 98.5-101.0% | 99.13% |
Residual Solvents | Ethyl Acetat: ≤0.5% Ethanol: ≤0.5% | 0.08% 0.12% |
PH | 4.5-5.5 | 5.3 |
Microbial Limits | Max 5*102 aerobes and fungl per 1g E. Coli: Negative Salmonella: Negative | Conforms |
Size of distributed particles | Pass 100μ m | Conforms |
Conclusion | Meet the requirements |