L-alanyl-L-glutamine also known as alanylglutamine, is a dipeptide molecule, consisting of L-glutamine and L-alanine, two amino acids. L-alanyl-L-glutamine is sometimes supplemented for prolonged physical exercise as it can enhance electrolyte absorption and improve endurance and performance. Tests on rodents suggest L-alanyl-L-glutamine is more successful at increasing muscular glutamine levels after supplementation than glutamine itself. This is because glutamine is absorbed better via the liver and intestines after supplementation. Since L-alanyl-L-glutamine is a dipeptide molecule it means that it contains more than one amino acid for the intestines to absorb, allowing glutamine to reach the muscles.

Adding L-alanyl-L-glutamine to any rehydration solution will be significantly more effective at increasing water and electrolyte absorption than consuming either a glutamine or glucose-containing solution. Current studies on L-alanyl-L-glutamine use a dose of 1-3g a day. Overdosage of L-alanyl-L-glutamine may result in chills, nausea and vomiting. Precautions need to be taken with patients who suffer from severe hepatic impairment, severe metabolic acidosis as it may contradict the medication. There are no reported side effects of the drug. Following the prescribed dosage of approximately 231 and 266 mg of L-alanyl-L-glutamine per pound of bodyweight per day for men and women.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

How to Take Alanylglutamine

Current studies on L-alanyl-L-glutamine use a dose of 1-3g a day. More research is needed to determine the optimal dose.

L-Alanyl-L-Glutamine supplementation may be similar to glutamine supplementation, in terms of dose, timing, and purpose.