Introduction
 

Rimonabant, a selective endocannabinoi (CB1) receptor antagonist, was initially developed as an anti-obesity drug. However, since the endogenous cannabinoi system (mediated by CB1 receptors) in the brain is known to play a part in nicotine reward, rimonabant was investigated as a potential aid to smoking cessation. Three large clinical trials involving smokers and quitters have been conducted. 

An experimental wonder drug, Rimonabant, helps you lose weight, quit smoking and it also helps protect your heart. Trials have shown that 33% of people on Rimonabant lost 10% of body weight and kept their weight down for two years - this is a record, no other diet drug has managed to keep a person's weight down for so long. The second 33% lost 5% of body weight and kept it down. As well as keeping you lean, the drug also helps you quit the smoking habit. This will be of great interest for many smokers who are afraid to give up because they say they will put on loads of weight if they do (young female smokers worry about this the most).